[HTML][HTML] Homology modeling in the time of collective and artificial intelligence

T Hameduh, Y Haddad, V Adam, Z Heger - Computational and Structural …, 2020 - Elsevier
Homology modeling is a method for building protein 3D structures using protein primary
sequence and utilizing prior knowledge gained from structural similarities with other …

DeepMSA: constructing deep multiple sequence alignment to improve contact prediction and fold-recognition for distant-homology proteins

C Zhang, W Zheng, SM Mortuza, Y Li, Y Zhang - Bioinformatics, 2020 - academic.oup.com
Motivation The success of genome sequencing techniques has resulted in rapid explosion
of protein sequences. Collections of multiple homologous sequences can provide critical …

DEEPCON: protein contact prediction using dilated convolutional neural networks with dropout

B Adhikari - Bioinformatics, 2020 - academic.oup.com
Motivation Exciting new opportunities have arisen to solve the protein contact prediction
problem from the progress in neural networks and the availability of a large number of …

PconsFam: an interactive database of structure predictions of Pfam families

J Lamb, AI Jarmolinska, M Michel… - Journal of molecular …, 2019 - Elsevier
At present, about half of the protein domain families lack a structural representative.
However, in the last decade, predicting contact maps and using these to model the tertiary …