Frontotemporal lobar degeneration

M Grossman, WW Seeley, AL Boxer, AE Hillis… - Nature Reviews …, 2023 - nature.com
Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …

Frontotemporal dementia

NT Olney, S Spina, BL Miller - Neurologic clinics, 2017 - neurologic.theclinics.com
Frontotemporal dementia (FTD) has undergone numerous changes in nomenclature and
categorization schemes since it was first described by Pick in 1892. Presently, FTD …

LATE-NC staging in routine neuropathologic diagnosis: an update

PT Nelson, EB Lee, MD Cykowski, I Alafuzoff… - Acta …, 2023 - Springer
An international consensus report in 2019 recommended a classification system for limbic-
predominant age-related TDP-43 encephalopathy neuropathologic changes (LATE-NC) …

Tau and tauopathies

T Arendt, JT Stieler, M Holzer - Brain research bulletin, 2016 - Elsevier
Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble
proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly …

A clinicopathological approach to the diagnosis of dementia

FM Elahi, BL Miller - Nature Reviews Neurology, 2017 - nature.com
The most definitive classification systems for dementia are based on the underlying
pathology which, in turn, is categorized largely according to the observed accumulation of …

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

M DeJesus-Hernandez, IR Mackenzie, BF Boeve… - Neuron, 2011 - cell.com
Several families have been reported with autosomal-dominant frontotemporal dementia
(FTD) and amyotrophic lateral sclerosis (ALS), genetically linked to chromosome 9p21 …

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

BT Hyman, CH Phelps, TG Beach, EH Bigio… - Alzheimer's & …, 2012 - Elsevier
A consensus panel from the United States and Europe was convened recently to update and
revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's …

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

K Rascovsky, JR Hodges, D Knopman, MF Mendez… - Brain, 2011 - academic.oup.com
Based on the recent literature and collective experience, an international consortium
developed revised guidelines for the diagnosis of behavioural variant frontotemporal …

National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

TJ Montine, CH Phelps, TG Beach, EH Bigio… - Acta …, 2012 - Springer
We present a practical guide for the implementation of recently revised National Institute on
Aging–Alzheimer's Association guidelines for the neuropathologic assessment of …

Molecular neuropathology of frontotemporal dementia: insights into disease mechanisms from postmortem studies

IRA Mackenzie, M Neumann - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinical syndrome with a heterogeneous molecular
basis. The past decade has seen the discovery of several new FTD‐causing genetic …