An imbalance of homeostasis in the retina leads to neuron loss and this eventually results in
a deterioration of vision. If the stress threshold is exceeded, different protective/survival …

Introduction In the last 25 years, topical prostaglandin analogues (PGAs) have emerged to
become first line and first choice therapeutic options in the management of glaucoma and …

Purpose: The interpretation of changes in serial intraocular pressure (IOP) measurements
are critical in the diagnosis and management of glaucoma. Differentiating true change from …

Introduction: Medical therapy of glaucoma aims to maintain the patient's visual function and
quality of life. This generally commences with monotherapy, but it is often difficult to reach …

The identification of similar three-dimensional (3D) amino acid patterns among different
proteins might be helpful to explain the polypharmacological profile of many currently used …

Introduction: The preservative-free (PF) fixed combination (FC) of tafluprost 0.0015%/timolol
0.5% is the newest member of the prostaglandin analogue/timolol FC class. Areas covered …

Glaucoma encompasses a group of optic neuropathies characterized by complex and often
elusive etiopathology, involvihttng neurodegeneration of the optic nerve in conjunction with …

Synthetic lethality, involving the simultaneous deactivation of two genes, disrupts cellular
functions or induces cell death. This study examines its role in cancer, focusing on focal …

Introduction Fixed-combination glaucoma medications have altered the paradigm of ocular
hypertension and glaucoma treatment and are in widespread use today. A comprehensive …

Background Ocular hypertension is one of the most underdiagnosed ocular abnormalities
among guinea pigs around the world. Objectives The current study investigates the effect of …