Combining nanomedicine and immunotherapy

Y Shi, T Lammers - Accounts of chemical research, 2019 - ACS Publications
Conspectus Nanomedicine holds significant potential to improve the efficacy of cancer
immunotherapy. Thus far, nanomedicines, ie, 1–100 (0) nm sized drug delivery systems …

Physical principles of nanoparticle cellular endocytosis

S Zhang, H Gao, G Bao - ACS nano, 2015 - ACS Publications
This review article focuses on the physiochemical mechanisms underlying nanoparticle
uptake into cells. When nanoparticles are in close vicinity to a cell, the interactions between …

Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Gold nanoparticles for in vitro diagnostics

W Zhou, X Gao, D Liu, X Chen - Chemical reviews, 2015 - ACS Publications
IVD test is a crucial component of clinical care that performs a diagnostic test on biological
samples that have been taken from a living body, such as blood, urine, and tissue.(1) Such …

Gold nanoparticles in chemical and biological sensing

K Saha, SS Agasti, C Kim, X Li, VM Rotello - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION Detection of chemical and biological agents plays a fundamental role in
biomedical, forensic and environmental sciences 1− 4 as well as in anti bioterrorism …

Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy

J Yao, M Yang, Y Duan - Chemical reviews, 2014 - ACS Publications
2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

Gold nanoparticles for biology and medicine

DA Giljohann, DS Seferos, WL Daniel… - Spherical Nucleic …, 2020 - api.taylorfrancis.com
Gold nanoparticles (AuNPs) have a rich history in chemistry, dating back to ancient R beg
glasses f an ov or decor er 150 y ati ears ago ve purpose oman times w s. The modern here …

Highly sensitive and multiplexed protein measurements

L Cohen, DR Walt - Chemical reviews, 2018 - ACS Publications
Proteins are involved in many biological processes. Misfolded, truncated, or mutated
proteins as well as over-or underexpressed proteins have been implicated in many …

Magnetoferritin nanoparticles for targeting and visualizing tumour tissues

K Fan, C Cao, Y Pan, D Lu, D Yang, J Feng… - Nature …, 2012 - nature.com
Engineered nanoparticles have been used to provide diagnostic,,, therapeutic, and
prognostic information, about the status of disease. Nanoparticles developed for these …

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

JE Dahlman, KJ Kauffman, Y Xing… - Proceedings of the …, 2017 - National Acad Sciences
Nucleic acid therapeutics are limited by inefficient delivery to target tissues and cells and by
an incomplete understanding of how nanoparticle structure affects biodistribution to off …