Current developments in gastric cancer: from molecular profiling to treatment strategy

M Alsina, V Arrazubi, M Diez, J Tabernero - … Reviews Gastroenterology & …, 2023 - nature.com
Gastric cancer and gastro-oesophageal junction cancer represent a global health-care
challenge. Despite the efficacy of improved chemotherapy and surgical options, these …

Intratumoral microbiota: roles in cancer initiation, development and therapeutic efficacy

L Yang, A Li, Y Wang, Y Zhang - Signal transduction and targeted …, 2023 - nature.com
Microorganisms, including bacteria, viruses, fungi, and other eukaryotes, play critical roles in
human health. An altered microbiome can be associated with complex diseases …

[HTML][HTML] Updates on global epidemiology, risk and prognostic factors of gastric cancer

WJ Yang, HP Zhao, Y Yu, JH Wang, L Guo… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Gastric cancer (GC) is defined as the primary epithelial malignancy derived from the
stomach, and it is a complicated and heterogeneous disease with multiple risk factors …

Cancer and the microbiome—influence of the commensal microbiota on cancer, immune responses, and immunotherapy

V Matson, CS Chervin, TF Gajewski - Gastroenterology, 2021 - Elsevier
The commensal microbiota has been implicated in the regulation of a diverse array of
physiological processes, both within the gastrointestinal tract and at distant tissue sites …

The microbiome, cancer, and cancer therapy

BA Helmink, MAW Khan, A Hermann… - Nature medicine, 2019 - nature.com
With the advent of next-generation sequencing, we have an unprecedented ability to study
tumor and host genomes as well as those of the vast array of microorganisms that exist …

Current challenges and best-practice protocols for microbiome analysis

R Bharti, DG Grimm - Briefings in bioinformatics, 2021 - academic.oup.com
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

[HTML][HTML] Human gut microbiome: hopes, threats and promises

PD Cani - Gut, 2018 - gut.bmj.com
The microbiome has received increasing attention over the last 15 years. Although gut
microbes have been explored for several decades, investigations of the role of …

Mapping the genomic diaspora of gastric cancer

KG Yeoh, P Tan - Nature reviews cancer, 2022 - nature.com
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
Pioneering genomic studies, focusing largely on primary GCs, revealed driver alterations in …

Aspects of gut microbiota and immune system interactions in infectious diseases, immunopathology, and cancer

V Lazar, LM Ditu, GG Pircalabioru, I Gheorghe… - Frontiers in …, 2018 - frontiersin.org
The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea,
and protozoans, bringing to the host organism a dowry of cells and genes more numerous …

Metabolic effects of dietary nitrate in health and disease

JO Lundberg, M Carlström, E Weitzberg - Cell metabolism, 2018 - cell.com
Nitric oxide (NO), generated from L-arginine and oxygen by NO synthases, is a pleiotropic
signaling molecule involved in cardiovascular and metabolic regulation. More recently, an …