Proton therapy treatments are based on a proton RBE (relative biological effectiveness)
relative to high-energy photons of 1.1. The use of this generic, spatially invariant RBE within …

In addition to the physical advantages (Bragg peak), the use of charged particles in cancer
therapy can be associated with distinct biological effects compared to X-rays. While heavy …

The biological effectiveness of proton beams relative to photon beams in radiation therapy
has been taken to be 1.1 throughout the history of proton therapy. While potentially …

Purpose The biological optimization of proton therapy can be achieved only through a
detailed evaluation of relative biological effectiveness (RBE) variations along the full range …

Proton therapy is increasingly being used as a radiation therapy modality. There is
uncertainty about the biological effectiveness of protons relative to photon therapies as it …

Background and Significance The application of heavy ion beams in cancer therapy must
account for the increasing relative biological effectiveness (RBE) with increasing penetration …

Introduction: The aim of the present study was to examine the RBE for early damage in an in
vivo mouse model, and the effect of the increased linear energy transfer (LET) towards the …

Purpose: Currently in proton radiation therapy, a constant relative biological effectiveness
(RBE) equal to 1.1 is assumed. The purpose of this study is to evaluate the impact of …

Proton therapy treatments are prescribed using a biological effectiveness relative to photon
therapy of 1.1, that is, proton beams are considered to be 10% more biologically effective …

With the current UK expansion of proton therapy there is a great opportunity for clinical
oncologists to develop a translational interest in the associated scientific base and clinical …