[HTML][HTML] Advancements in clinical aspects of targeted therapy and immunotherapy in breast cancer

F Ye, S Dewanjee, Y Li, NK Jha, ZS Chen, A Kumar… - Molecular cancer, 2023 - Springer
Breast cancer is the second leading cause of death for women worldwide. The
heterogeneity of this disease presents a big challenge in its therapeutic management …

High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy

B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

[HTML][HTML] Cancer DNA vaccines: current preclinical and clinical developments and future perspectives

A Lopes, G Vandermeulen, V Préat - Journal of Experimental & Clinical …, 2019 - Springer
The recent developments in immuno-oncology have opened an unprecedented avenue for
the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now considered …

[HTML][HTML] Therapeutic vaccines for breast cancer: Has the time finally come?

C Corti, PPMB Giachetti, AMM Eggermont… - European Journal of …, 2022 - Elsevier
The ability to exploit the immune system as a weapon against cancer has revolutionised the
treatment of cancer patients, especially through immune checkpoint inhibitors (ICIs) …

[HTML][HTML] Breast cancer vaccines: disappointing or promising?

SY Zhu, KD Yu - Frontiers in Immunology, 2022 - frontiersin.org
Breast cancer has become the most commonly diagnosed cancer globally. The relapse and
metastasis of breast cancer remain a great challenge despite advances in chemotherapy …

[HTML][HTML] Developments in viral vector-based vaccines

T Ura, K Okuda, M Shimada - Vaccines, 2014 - mdpi.com
Viral vectors are promising tools for gene therapy and vaccines. Viral vector-based vaccines
can enhance immunogenicity without an adjuvant and induce a robust cytotoxic T …

Cancer vaccines

LH Butterfield - Bmj, 2015 - bmj.com
Cancer vaccines are designed to promote tumor specific immune responses, particularly
cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines …

DNA vaccine for cancer immunotherapy

B Yang, J Jeang, A Yang, TC Wu… - Human vaccines & …, 2014 - Taylor & Francis
DNA vaccination has emerged as an attractive immunotherapeutic approach against cancer
due to its simplicity, stability, and safety. Results from numerous clinical trials have …

[HTML][HTML] COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models

A Conforti, E Marra, F Palombo, G Roscilli, M Ravà… - Molecular Therapy, 2022 - cell.com
The COVID-19 pandemic caused by SARS-CoV-2 has made the development of safe and
effective vaccines a critical priority. To date, four vaccines have been approved by European …

[HTML][HTML] Engineering neoantigen vaccines to improve cancer personalized immunotherapy

Z Liu, J Lv, Q Dang, L Liu, S Weng, L Wang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Immunotherapy treatments harnessing the immune system herald a new era of personalized
medicine, offering considerable benefits for cancer patients. Over the past years, tumor …