[HTML][HTML] Navigating oligodendrocyte precursor cell aging in brain health

F Leenders, L Koole, H Slaets, A Tiane… - Mechanisms of Ageing …, 2024 - Elsevier
Oligodendrocyte precursor cells (OPCs) comprise 5–8% of the adult glial cell population and
stand out as the most proliferative cell type in the central nervous system (CNS). OPCs are …

Disease-modifying strategies: Targeting protein kinases in multiple sclerosis and other autoimmune disorders

FF Konen, N Möhn, T Witte, M Schefzyk, M Wiestler… - Autoimmunity …, 2025 - Elsevier
A wide variety of immunomodulatory therapies are already available for the treatment of
multiple sclerosis (MS). Through fundamental insights from basic research with a gain of …

Oligodendrocyte Progenitors in Glial Scar: A Bet on Remyelination

D Marangon, JH Castro e Silva, V Cerrato, E Boda… - Cells, 2024 - mdpi.com
á Oligodendrocyte progenitor cells (OPCs) represent a subtype of glia, giving rise to
oligodendrocytes, the myelin-forming cells in the central nervous system (CNS). While OPCs …

[HTML][HTML] Promoting remyelination in central nervous system diseases: potentials and prospects of natural products and herbal medicine

H Zhu, E Hu, X Guo, Z Yuan, H Jiang, W Zhang… - Pharmacological …, 2024 - Elsevier
Myelin damage is frequently associated with central nervous system (CNS) diseases and is
a critical factor influencing neurological function and disease prognosis. Nevertheless, the …

[HTML][HTML] Understanding the Complex Dynamics of Immunosenescence in Multiple Sclerosis: From Pathogenesis to Treatment

M Neațu, A Hera-Drăguț, I Ioniță, A Jugurt… - Biomedicines, 2024 - mdpi.com
Immunosenescence, the gradual deterioration of immune function with age, holds profound
implications for our understanding and management of multiple sclerosis (MS), a chronic …

[PDF][PDF] Siponimod-loaded extracellular vesicles to stimulate remyelination in the central nervous system

V Gratpain - 2024 - dial.uclouvain.be
Once it became apparent that extracellular vesicles were involved in local and systemic cell
communication [250, 356], extensive studies were conducted to elucidate their role in …