DNA-dependent protease activity of human Spartan facilitates replication of DNA–protein crosslink-containing DNA
Mutations in SPARTAN are associated with early onset hepatocellular carcinoma and
progeroid features. A regulatory function of Spartan has been implicated in DNA damage …
progeroid features. A regulatory function of Spartan has been implicated in DNA damage …
Oxidative DNA-protein crosslinks formed in mammalian cells by abasic site lyases involved in DNA repair
JL Quiñones, U Thapar, SH Wilson, DA Ramsden… - DNA repair, 2020 - Elsevier
Free radical attack on C1′ of deoxyribose forms the oxidized abasic (AP) site 2-
deoxyribonolactone (dL). In vitro, dL traps the major base excision DNA repair enzyme DNA …
deoxyribonolactone (dL). In vitro, dL traps the major base excision DNA repair enzyme DNA …
Uloga proteaze SPRTN u popravku DNA nakon oštećenja uzrokovanih kovalentnim vezanjem proteina
M Glumac - 2023 - repozitorij.mefst.unist.hr
Sažetak DPC-ovi predstavljaju jedan od najčešćih, ali i najmanje istraženih tipova oštećenja
DNA. Njihovo istraživanje se intenziviralo tek otkrićem proteaza ovisnih o DNA, zaduženih …
DNA. Njihovo istraživanje se intenziviralo tek otkrićem proteaza ovisnih o DNA, zaduženih …
Uloga p97/VCP AAA ATPaze u popravku unakrsnog vezanja DNA i proteina
V Dakić - 2020 - repozitorij.pmf.unizg.hr
Sažetak Unakrsna veza između DNA i proteina (engl. DNA-protein crosslink, DPC) je tip
oštećenja DNA koje nastaje kao posljedica stvaranja ireverzibilne kovalentne veze između …
oštećenja DNA koje nastaje kao posljedica stvaranja ireverzibilne kovalentne veze između …
Demethylation Therapy As A Novel Treatment For Human Papilloma Virus-Associated Head And Neck Cancer
M Hajek - 2017 - elischolar.library.yale.edu
azacytidine (5-aza) and its structural analog 5-aza-2'-deoxycytidine (decitabine) are
demethylating agents currently used to treat myelodysplastic syndrome and acute myeloid …
demethylating agents currently used to treat myelodysplastic syndrome and acute myeloid …