Targeting biomolecular condensation and protein aggregation against cancer

JL Silva, D Foguel, VF Ferreira, TCRG Vieira… - Chemical …, 2023 - ACS Publications
Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

[HTML][HTML] Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer

P Kumar, S Gupta, BC Das - Translational oncology, 2024 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) are the most devastating diseases in
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …

Immunoexpression of p53 mutant-type in Iranian patients with primary and recurrence oral squamous cell carcinoma

H Daneste, A Sadeghzadeh, M Mokhtari… - European Journal …, 2022 - pmc.ncbi.nlm.nih.gov
Mutations in tumor suppressor p53 protein can occur at different phases of malignant
transformation and affect the patient's prognosis. This study aimed to evaluate the …

Immune landscape and immunotherapy options in cervical carcinoma

K Kousar, T Ahmad, F Naseer, S Kakar, S Anjum - Cancers, 2022 - mdpi.com
Simple Summary Cervical cancer is one of the most common cancers with a high mortality
rate, especially in women of reproductive age. A lot of treatment modalities are being used in …

Pharmacological impact of microRNAs in head and neck squamous cell carcinoma: prevailing insights on molecular pathways, diagnosis, and nanomedicine …

B Bhattacharjee, AF Syeda, D Rynjah… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma is a disease that most commonly produce tumours
from the lining of the epithelial cells of the lips, larynx, nasopharynx, mouth, or oro-pharynx. It …

[HTML][HTML] Novel Predictive Biomarkers in the Head and Neck Squamous Cell Carcinoma (HNSCC)

M Miniuk, J Reszeć-Giełażyn, P Bortnik… - Journal of Clinical …, 2024 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide, characterized by high aggressiveness and frequent metastasis to regional lymph …

Curcumin: A Potential Weapon in the Prevention and Treatment of Head and Neck Cancer

K Veselá, Z Kejík, M Masařík, P Babula… - ACS Pharmacology & …, 2024 - ACS Publications
Head and neck cancers (HNC) are aggressive, difficult-to-treat tumors that can be caused by
genetic factors but mainly by lifestyle or infection caused by the human papillomavirus. As …

[HTML][HTML] Molecular targeted therapies for cutaneous squamous cell carcinoma: recent developments and clinical implications

H Singh, H Chopra, I Singh, S Mohanto, MG Ahmed… - EXCLI …, 2024 - ncbi.nlm.nih.gov
Abstract Cutaneous Squamous Cell Carcinoma (cSCC) is a common and potentially fatal
type of skin cancer that poses a significant threat to public health and has a high prevalence …

The roles of protein ubiquitination in tumorigenesis and targeted drug discovery in lung cancer

Z Ye, J Yang, H Jiang, X Zhan - Frontiers in Endocrinology, 2023 - frontiersin.org
The malignant lung cancer has a high morbidity rate and very poor 5-year survival rate.
About 80%-90% of protein degradation in human cells is occurred through the ubiquitination …

Administration of 4‑hexylresorcinol increases p53‑mediated transcriptional activity in oral cancer cells with the p53 mutation

YJ Kang, WG Yang, WS Chae, DW Kim… - Oncology …, 2022 - spandidos-publications.com
The p53 mutation is inherent in over 50% of human cancers. In head and neck squamous
cell carcinoma, the p53 mutation is associated with a poor prognosis. 4‑Hexylresorcinol …