Understanding myeloperoxidase-induced damage to HDL structure and function in the vessel wall: implications for HDL-based therapies
Atherosclerosis is a disease of increased oxidative stress characterized by protein and lipid
modifications in the vessel wall. One important oxidative pathway involves reactive …
modifications in the vessel wall. One important oxidative pathway involves reactive …
Apolipoprotein AI mimetics
Apolipoprotein AI mimetics : Current Opinion in Lipidology Apolipoprotein AI mimetics :
Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe Get new …
Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe Get new …
Anti-inflammatory mechanisms of apolipoprotein AI mimetic peptide in acute respiratory distress syndrome secondary to sepsis
OF Sharifov, X Xu, A Gaggar, WE Grizzle, VK Mishra… - PLoS …, 2013 - journals.plos.org
Acute respiratory distress syndrome (ARDS) due to sepsis has a high mortality rate with
limited treatment options. High density lipoprotein (HDL) exerts innate protective effects in …
limited treatment options. High density lipoprotein (HDL) exerts innate protective effects in …
[HTML][HTML] Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1
D He, M Zhao, C Wu, W Zhang, C Niu, B Yu, J Jin, L Ji… - Redox biology, 2018 - Elsevier
Disruption of endothelial monolayer integrity is the primary instigating factor for many
cardiovascular diseases. High density lipoprotein (HDL) oxidized by heme enzyme …
cardiovascular diseases. High density lipoprotein (HDL) oxidized by heme enzyme …
Carboxyl-terminal cleavage of apolipoprotein AI by human mast cell chymase impairs its anti-inflammatory properties
SD Nguyen, K Maaninka, J Lappalainen… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Apolipoprotein AI (apoA-I) has been shown to possess several atheroprotective
functions, including inhibition of inflammation. Protease-secreting activated mast cells reside …
functions, including inhibition of inflammation. Protease-secreting activated mast cells reside …
The apoA-I mimetic peptide 4F protects apolipoprotein AI from oxidative damage
CR White, G Datta, L Wilson, MN Palgunachari… - Chemistry and physics …, 2019 - Elsevier
High density lipoprotein (HDL) is prone to modification by the oxidizing and chlorinating
agent hypochlorite anion (OCl−). Oxidation of apolipoprotein (apo) AI, the major protein in …
agent hypochlorite anion (OCl−). Oxidation of apolipoprotein (apo) AI, the major protein in …
Cholesterol Efflux Capacity of Apolipoprotein A‐I Varies with the Extent of Differentiation and Foam Cell Formation of THP‐1 Cells
K Yano, R Ohkawa, M Sato, A Yoshimoto… - Journal of …, 2016 - Wiley Online Library
Apolipoprotein A‐I (apoA‐I), the main protein component of high‐density lipoprotein (HDL),
has many protective functions against atherosclerosis, one of them being cholesterol efflux …
has many protective functions against atherosclerosis, one of them being cholesterol efflux …
The structure/function of apoprotein AI mimetic peptides: an update
GS Getz, CA Reardon - Current Opinion in Endocrinology …, 2014 - journals.lww.com
The structure/function of apoprotein AI mimetic peptides: a... : Current Opinion in Endocrinology,
Diabetes and Obesity The structure/function of apoprotein AI mimetic peptides: an update …
Diabetes and Obesity The structure/function of apoprotein AI mimetic peptides: an update …
L-4F inhibits lipopolysaccharide-mediated activation of primary human neutrophils
OF Sharifov, X Xu, A Gaggar, EM Tabengwa, CR White… - Inflammation, 2014 - Springer
Abstract Human apolipoprotein AI (apoA-I) mimetic L-4F inhibits acute inflammation in
endotoxemic animals. Since neutrophils play a crucial role in septic inflammation, we …
endotoxemic animals. Since neutrophils play a crucial role in septic inflammation, we …
Effects of apoA-I mimetic peptide L-4F in LPS-mediated inflammation
OF Sharifov, GM Anantharamaiah, H Gupta - Apolipoprotein Mimetics in …, 2015 - Springer
Despite recent advances in antimicrobial and anti-inflammatory therapy, sepsis continues to
be a major cause of death in hospitalized patients. To date few interventions have been …
be a major cause of death in hospitalized patients. To date few interventions have been …