Idiopathic pulmonary fibrosis (IPF) is an interstitial disease of unknown etiology
characterized by progressive pulmonary fibrosis. Pirfenidone and nintedanib are the only …

Prognosis of patients with cystic fibrosis (CF) varies extensively despite recent advances in
targeted therapies that improve CF transmembrane conductance regulator (CFTR) function …

Direct delivery to the lung via inhalation is arguably one of the most logical approaches to
treat lung cancer using drugs. However, despite significant efforts and investment in this …

Nasal mucosa injury can be caused by trauma, radiotherapy, chronic infection such as
sinusitis, and post sinus surgery. The rate of healing and its treatment are important in the …

Acute lung injury (ALI) is a severe clinical condition with high morbidity and mortality that
usually results in the development of multiple organ dysfunction. The complex …

Background The aim of this study was to investigate the effects of MSCs and MSC-
expressing ANGPT1 (MSC-pANGPT1) treatment via aerosolisation in alleviating the asthma …

Interstitial lung diseases (ILDs) are a heterogeneous group of pulmonary disorders
characterized by variable degrees of inflammation, interstitial thickening, and fibrosis …

Background and objectives: Drug delivery by nebulization has become a crucial strategy for
treating different respiratory and lung diseases. Emerging evidence implicates stem cell …

器官纤维化以细胞外基质(ECM) 过度沉积为特征, 是慢性脏器疾病发展为癌症的中间病理过程.
目前尚无有效的抗纤维化方法. 间充质干细胞(MSCs) 作为多能干细胞, 不仅可通过增殖分化 …

Airway stem/progenitor epithelial cells (AECs) are notable for their differentiation capacities
in response to lung injury. Our previous finding highlighted the regenerative capacity of …