Periodontitis is an inflammatory disease of oxidative stress: We should treat it that way

FSC Sczepanik, ML Grossi, M Casati… - Periodontology …, 2020 - Wiley Online Library
Periodontitis is a highly prevalent disease. As it progresses, it causes serious morbidity in
the form of periodontal abscesses and tooth loss and, in the latter stages, pain. It is also now …

Mucosal applications of poloxamer 407-based hydrogels: An overview

E Giuliano, D Paolino, M Fresta, D Cosco - Pharmaceutics, 2018 - mdpi.com
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …

[HTML][HTML] Smart stimuli-responsive hydrogels for drug delivery in periodontitis treatment

Y Wang, J Li, M Tang, C Peng, G Wang, J Wang… - Biomedicine & …, 2023 - Elsevier
Periodontitis is a chronic inflammatory disease initiated by pathogenic biofilms and host
immunity that damages tooth-supporting tissues, including the gingiva, periodontal ligament …

Local drug delivery systems in the management of periodontitis: A scientific review

HR Rajeshwari, D Dhamecha, S Jagwani… - Journal of Controlled …, 2019 - Elsevier
Periodontitis (PD) is a microbial disease of tooth supporting tissues that results in
progressive destruction of surrounding soft and hard tissues with eventual tooth mobility and …

Evaluation and characterization of curcumin-β-cyclodextrin and cyclodextrin-based nanosponge inclusion complexation

H Mashaqbeh, R Obaidat, N Al-Shar'i - Polymers, 2021 - mdpi.com
Cyclodextrin polymers and cyclodextrin-based nanosponges have been widely investigated
for increasing drug bioavailability. This study examined curcumin's complexation stability …

Local drug delivery systems as therapeutic strategies against periodontitis: A systematic review

Y Wei, Y Deng, S Ma, M Ran, Y Jia, J Meng… - Journal of Controlled …, 2021 - Elsevier
Periodontitis is a chronic inflammation of the soft tissue surrounding and supporting the
teeth, which causes periodontal structural damage, alveolar bone resorption, and even tooth …

An overview on thermosensitive oral gel based on poloxamer 407

Y Chen, JH Lee, M Meng, N Cui, CY Dai, Q Jia, ES Lee… - Materials, 2021 - mdpi.com
In this review, we describe the application of thermosensitive hydrogels composed of
poloxamer in medicine, especially for oral cavities. Thermosensitive hydrogels remain fluid …

Emerging applications of drug delivery systems in oral infectious diseases prevention and treatment

J Liang, X Peng, X Zhou, J Zou, L Cheng - Molecules, 2020 - mdpi.com
The oral cavity is a unique complex ecosystem colonized with huge numbers of
microorganism species. Oral cavities are closely associated with oral health and …

Rational design of bioactive hydrogels toward periodontal delivery: from pathophysiology to therapeutic applications

Y Yin, S Yang, D Ai, H Qin, Y Sun, X Xia… - Advanced Functional …, 2023 - Wiley Online Library
Periodontitis is a biofilm‐induced, host‐mediated inflammatory disease that results in
periodontal tissue destruction. The design of functional biomaterials based on disease …

[HTML][HTML] A tunable and injectable local drug delivery system for personalized periodontal application

B Wang, J Wang, J Shao, PHJ Kouwer… - Journal of Controlled …, 2020 - Elsevier
In periodontal treatment, patient differences in disease phenotype and treatment responses
are well documented. Therefore, therapy duration and dosage should be tailored to the …