Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

Innate lymphoid cells and cancer

N Jacquelot, C Seillet, E Vivier, GT Belz - Nature Immunology, 2022 - nature.com
The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

[HTML][HTML] Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

I Leonardi, IH Gao, WY Lin, M Allen, XV Li, WD Fiers… - Cell, 2022 - cell.com
Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …

The intestinal microbiota fuelling metabolic inflammation

H Tilg, N Zmora, TE Adolph, E Elinav - Nature Reviews Immunology, 2020 - nature.com
Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

Interaction between the microbiota, epithelia, and immune cells in the intestine

H Kayama, R Okumura, K Takeda - Annual review of …, 2020 - annualreviews.org
The gastrointestinal tract harbors numerous commensal bacteria, referred to as the
microbiota, that benefit host health by digesting dietary components and eliminating …

[HTML][HTML] Innate lymphoid cells: 10 years on

E Vivier, D Artis, M Colonna, A Diefenbach, JP Di Santo… - Cell, 2018 - cell.com
Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …

IL-10 family cytokines IL-10 and IL-22: from basic science to clinical translation

W Ouyang, A O'Garra - Immunity, 2019 - cell.com
Cytokines are among the most important effector and messenger molecules in the immune
system. They profoundly participate in immune responses during infection and inflammation …

Gut microbiota in cancer immune response and immunotherapy

CB Zhou, YL Zhou, JY Fang - Trends in cancer, 2021 - cell.com
The gastrointestinal tract (GIT) is the largest immune organ and maintains systemic immune
homeostasis in the presence of bacterial challenge. Immune elimination and immune …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

[HTML][HTML] The role of IL-22 in intestinal health and disease

ME Keir, T Yi, TT Lu, N Ghilardi - Journal of Experimental Medicine, 2020 - rupress.org
The role of IL-22 in intestinal health and disease | Journal of Experimental Medicine |
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