The role of fibrinogen in traumatic brain injury: from molecular pathological mechanisms to clinical management

S Peng, K Lv - European Journal of Trauma and Emergency Surgery, 2023 - Springer
Fibrinogen is the substrate of plasma coagulation. It plays an important role in the formation
of reticular network, which is crucial to the strength and stability of blood clots. In addition to …

Management of severe traumatic brain injury in pediatric patients

A Lui, KK Kumar, GA Grant - Frontiers in toxicology, 2022 - frontiersin.org
The optimal management of severe traumatic brain injury (TBI) in the pediatric population
has not been well studied. There are a limited number of research articles studying the …

Gastrointestinal dysfunction criteria in critically ill children: the PODIUM consensus conference

KV Typpo, SY Irving, JM Prince, N Pathan… - Pediatrics, 2022 - publications.aap.org
CONTEXT Prior criteria to define pediatric multiple organ dysfunction syndrome (MODS) did
not include gastrointestinal dysfunction. OBJECTIVES Our objective was to evaluate current …

Pediatric severe traumatic brain injury mortality prediction determined with machine learning-based modeling

M Daley, S Cameron, SL Ganesan, MA Patel… - Injury, 2022 - Elsevier
Introduction Severe traumatic brain injury (sTBI) is a leading cause of mortality in children.
As clinical prognostication is important in guiding optimal care and decision making, our …

Application of coagulation parameters at the time of necrotizing enterocolitis diagnosis in surgical intervention and prognosis

W Feng, J Hou, X Die, J Sun, Z Guo, W Liu, Y Wang - BMC pediatrics, 2022 - Springer
Purpose It has been shown that abnormalities of coagulation and fibrinolysis system are
involved in the pathogenesis of necrotizing enterocolitis (NEC), but not well studied …

Predictors of In-hospital mortality for road traffic accident-related severe traumatic brain injury

CH Chen, YW Hsieh, JF Huang, CP Hsu… - Journal of personalized …, 2021 - mdpi.com
(1) Background: Road traffic accidents (RTAs) are the leading cause of pediatric traumatic
brain injury (TBI) and are associated with high mortality. Few studies have focused on RTA …

[HTML][HTML] Effects of Yunanan Baiyao adjunct therapy on postoperative recovery and clinical prognosis of patients with traumatic brain injury: a randomized controlled …

L Chen, H Jiang, G Xing, B Guan, Y Yang, A Ahmed… - Phytomedicine, 2021 - Elsevier
Background Effective therapies are needed to prevent the secondary injury and poor
prognosis associated with emergency craniotomy of traumatic brain injury (TBI) …

Predictors of in-hospital mortality for school-aged children with severe traumatic brain injury

CC Chen, CPC Chen, CH Chen, YW Hsieh, CY Chung… - Brain sciences, 2021 - mdpi.com
Traumatic brain injury (TBI) is the leading cause of mortality in children. There are few
studies focused on school-aged children with TBI. We conducted this study to identify the …

Early coagulopathy in children with isolated blunt head injury is associated with mortality and poor neurological outcomes

V James, SL Chong, SS Shetty, GY Ong - Journal of Neurosurgery …, 2020 - thejns.org
OBJECTIVE Traumatic brain injury (TBI) is the leading cause of long-term disability and
death in children and adolescents globally. Long-term adverse outcomes, including …

[HTML][HTML] Association of initial assessment variables and mortality in severe pediatric traumatic brain injury

KC Bergus, KN Patterson, L Asti, J Bricker… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Background Predictive scales have been used to prognosticate long-term outcomes of
traumatic brain injury (TBI), but gaps remain in predicting mortality using initial trauma …