Agnostic sequencing for detection of viral pathogens

NPG Gauthier, SD Chorlton, M Krajden… - Clinical microbiology …, 2023 - Am Soc Microbiol
The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …

Making waves: Wastewater surveillance of SARS-CoV-2 in an endemic future

F Wu, WL Lee, H Chen, X Gu, F Chandra, F Armas… - Water Research, 2022 - Elsevier
Wastewater-based surveillance (WBS) has been widely used as a public health tool to
monitor the emergence and spread of SARS-CoV-2 infections in populations during the …

Multiple introductions of SARS-CoV-2 alpha and delta variants into white-tailed deer in Pennsylvania

AD Marques, S Sherrill-Mix, JK Everett, H Adhikari… - MBio, 2022 - Am Soc Microbiol
The SARS-CoV-2 pandemic began by viral spillover from animals to humans; today multiple
animal species are known to be susceptible to infection. White-tailed deer, Odocoileus …

[HTML][HTML] City-wide wastewater genomic surveillance through the successive emergence of SARS-CoV-2 Alpha and Delta variants

FS Brunner, MR Brown, I Bassano, H Denise… - Water research, 2022 - Elsevier
Genomic surveillance of SARS-CoV-2 has provided a critical evidence base for public
health decisions throughout the pandemic. Sequencing data from clinical cases has helped …

COVID-19 monitoring with sparse sampling of sewered and non-sewered wastewater in urban and rural communities

DL Wannigama, M Amarasiri, P Hongsing, C Hurst… - Iscience, 2023 - cell.com
Equitable SARS-CoV-2 surveillance in low-resource communities lacking centralized
sewers is critical as wastewater-based epidemiology (WBE) progresses. However, large …

SARS-CoV-2 exposure in Norway rats (Rattus norvegicus) from New York city

Y Wang, J Lenoch, D Kohler, TJ DeLiberto, CY Tang… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Millions of Norway rats (Rattus norvegicus) inhabit New York City (NYC),
presenting the potential for transmission of severe acute respiratory syndrome coronavirus 2 …

From Alpha to Omicron BA. 2: New digital RT-PCR approach and challenges for SARS-CoV-2 VOC monitoring and normalization of variant dynamics in wastewater

S Wurtzer, M Levert, E Dhenain, H Accrombessi… - Science of the Total …, 2022 - Elsevier
Throughout the COVID-19 pandemic, new variants have continuously emerged and spread
in populations. Among these, variants of concern (VOC) have been the main culprits of …

Highly sensitive wastewater surveillance of SARS-CoV-2 variants by targeted next-generation amplicon sequencing provides early warning of incursion in Victoria …

JE Merrett, M Nolan, L Hartman, N John… - Applied and …, 2024 - journals.asm.org
The future of the COVID pandemic and its public health and societal impact will be
determined by the profile and spread of emerging variants and the timely identification and …

[HTML][HTML] SARS-CoV-2 concentration in wastewater consistently predicts trends in COVID-19 case counts by at least two days across multiple WWTP scales

CL Swift, M Isanovic, KEC Velez, RS Norman - Environmental Advances, 2023 - Elsevier
Wastewater surveillance of SARS-CoV-2 has proven instrumental in mitigating the spread of
COVID-19 by providing an economical and equitable approach to disease surveillance …

Baseline sequencing surveillance of public clinical testing, hospitals, and community wastewater reveals rapid emergence of SARS-CoV-2 omicron variant of concern …

MF Smith, SC Holland, MB Lee, JC Hu, NC Pham… - Mbio, 2023 - Am Soc Microbiol
The adaptive evolution of SARS-CoV-2 variants is driven by selection for increased viral
fitness in transmissibility and immune evasion. Understanding the dynamics of how an …