Importance Rates of bilateral mastectomy continue to increase in average-risk women with
unilateral in situ and invasive breast cancer. Contralateral prophylactic mastectomy rates …

The uptake of contralateral prophylactic mastectomy (CPM) has increased steadily over the
last twenty years in women of all age groups and breast cancer stages. Since contralateral …

Importance The benefit of bilateral mastectomy for women with unilateral breast cancer in
terms of deaths from breast cancer has not been shown. Objectives To estimate the 20-year …

Background We sought to estimate the annual risk and 25-year cumulative risk of
contralateral breast cancer among women with stage 0–III unilateral breast cancer. Methods …

Background Prediction of contralateral breast cancer (CBC) risk is challenging due to
moderate performances of the known risk factors. We aimed to improve our previous risk …

PURPOSE The absolute cumulative risk of contralateral breast cancer (CBC) for patients
with BRCA1/2 variants is unknown. The purpose of this study was to develop a CBC risk …

Purpose To evaluate the association between a previously published 313 variant–based
breast cancer (BC) polygenic risk score (PRS313) and contralateral breast cancer (CBC) …

After a diagnosis of unilateral breast cancer, increasing numbers of patients are requesting
contralateral prophylactic mastectomy (CPM), the surgical removal of the healthy breast after …

Annual surveillance mammography is recommended for breast cancer survivors on the
basis of observational studies and meta-analyses showing reduced breast cancer mortality …

Simple Summary Ductal carcinoma in situ (DCIS) is a potential precursor to invasive breast
cancer (IBC). Although in many women DCIS will never become breast cancer, almost all …