Global levels of obesity are reaching epidemic proportions, leading to a dramatic increase in incidence of secondary diseases and the significant economic burden associated with their …
A Moya-Pérez, A Neef, Y Sanz - PloS one, 2015 - journals.plos.org
Background/Objectives The role of intestinal dysbiosis in obesity-associated systemic inflammation via the cross-talk with peripheral tissues is under debate. Our objective was to …
S Della Torre - Frontiers in endocrinology, 2020 - frontiersin.org
There is extensive evidence supporting the interplay between metabolism and immune response, that have evolved in close relationship, sharing regulatory molecules and …
G Ghigliotti, C Barisione, S Garibaldi, P Fabbi… - Inflammation, 2014 - Springer
Adipose tissue inflammation mediates the association between excessive body fat accumulation and several chronic inflammatory diseases. A high prevalence of obesity …
M Gao, Y Ma, D Liu - PloS one, 2015 - journals.plos.org
High-fat diet (HFD) has been applied to a variety of inbred mouse strains to induce obesity and obesity related metabolic complications. In this study, we determined HFD induced …
B Biadgo, M Melku, SM Abebe… - … , metabolic syndrome and …, 2016 - Taylor & Francis
Background Diabetes mellitus is (DM) a global public health problem and a complex disease characterized by chronic hyperglycemia that leads to long-term macrovascular and …
Y Sanz, A Moya-Pérez - … endocrinology: The microbiota-gut-brain axis in …, 2014 - Springer
Interactions between metabolism and immunity play a pivotal role in the development of obesity-associated chronic co-morbidities. Obesity involves impairment of immune function …
PK Krajewski, Ł Matusiak, E von Stebut, M Schultheis… - Life, 2021 - mdpi.com
The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients' quality of life (QoL). The aim of this study was …
DY Oh, JM Olefsky - Nature reviews Drug discovery, 2016 - nature.com
The prevalence of obesity and type 2 diabetes (T2D) is increasing worldwide, and these two metabolic disorders are closely linked. Lifestyle modification, including weight loss and …