The maturation of high-throughput short-read sequencing technology over the past two
decades has shaped the way genomes are studied. Recently, single-molecule, long-read …

Liquid biopsy with circulating tumor DNA (ctDNA) profiling by next-generation sequencing
holds great promise to revolutionize clinical oncology. It relies on the basis that ctDNA …

Abstract The Oxford Nanopore (ONT) platform provides portable and rapid genome
sequencing, and its ability to natively profile DNA methylation without complex sample …

Cell‐free DNA (cfDNA) can be isolated and sequenced from blood and/or urine of cancer
patients. Conventional short‐read sequencing lacks deployability and speed and can be …

Over the past decade, nanopore sequencing has experienced significant advancements
and changes, transitioning from an initially emerging technology to a significant instrument …

Simple Summary This review aims to highlight the usage of circulating tumour DNA and
circulating tumour cells in various manners for the care of cancer patients. The different …

The recent development of high-throughput sequencing platforms provided impressive
insights into the field of human genetics and contributed to considering structural variants …

Liquid biopsies have emerged as a promising tool for the detection of metastases as well as
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …

Background Molecular brain tumor diagnosis is usually dependent on tissue biopsies or
resections. This can pose several risks associated with anesthesia or neurosurgery …

Since the development of Sanger sequencing in 1977, sequencing technology has played a
pivotal role in molecular biology research by enabling the interpretation of biological genetic …