Monocytes in tumorigenesis and tumor immunotherapy

X Chen, Y Li, H Xia, YH Chen - Cells, 2023 - mdpi.com
Monocytes are highly plastic innate immune cells that display significant heterogeneity
during homeostasis, inflammation, and tumorigenesis. Tumor-induced systemic and local …

The tumor-immune ecosystem in shaping metastasis

Y Gao, JM Rosen, XHF Zhang - American Journal of …, 2023 - journals.physiology.org
A better understanding of the mechanisms regulating cancer metastasis is critical to develop
new therapies and decrease mortality. Emerging evidence suggests that the interactions …

The glycocalyx and immune evasion in cancer

S Ghasempour, SA Freeman - The FEBS Journal, 2023 - Wiley Online Library
In order to establish malignant lesions, tumors must first evade their detection by immune
cells. Tumors achieve this by embellishing and tailoring their glycocalyx, a network of …

Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs

C Deng, Y Xu, H Chen, X Zhu, L Huang, Z Chen, H Xu… - Cell Reports, 2024 - cell.com
The premetastatic niche (PMN) contributes to lung-specific metastatic tropism in
osteosarcoma. However, the crosstalk between primary tumor cells and lung stromal cells is …

[HTML][HTML] Blocking the HGF-MET pathway induces resolution of neutrophilic inflammation by promoting neutrophil apoptosis and efferocytosis

FB Felix, J Dias, JP Vago, DG Martins… - Pharmacological …, 2023 - Elsevier
Inflammation resolution is an active process that involves cellular events such as apoptosis
and efferocytosis, which are key steps in the restoration of tissue homeostasis. Hepatocyte …