R Bharti, G Dey, M Mandal - Cancer letters, 2016 - Elsevier
Abstract Interleukin-6 (IL-6) is a cytokine present in tumor microenvironment. Elevated level of IL-6 is associated with cancer cell proliferation, angiogenesis and metastasis through …
L Bonapace, MM Coissieux, J Wyckoff, KD Mertz… - Nature, 2014 - nature.com
Secretion of C–C chemokine ligand 2 (CCL2) by mammary tumours recruits CCR2- expressing inflammatory monocytes to primary tumours and metastatic sites, and CCL2 …
EJ Ekström, C Bergenfelz, V von Bülow, F Serifler… - Molecular cancer, 2014 - Springer
Background Wnt proteins are important for developmental processes and certain diseases. WNT5A is a non-canonical Wnt protein that previously has been shown to play a role in the …
RD Pereira, NE De Long, RC Wang… - BioMed research …, 2015 - Wiley Online Library
Proper placental development and function are central to the health of both the mother and the fetus during pregnancy. A critical component of healthy placental function is the proper …
C Dominguez, JM David, C Palena - Seminars in cancer biology, 2017 - Elsevier
Tumor growth and progression are the products of complex signaling networks between different cell types within the tumor and its surrounding stroma. In particular, established …
K Gertz, G Kronenberg, RE Kälin, T Baldinger… - Brain, 2012 - academic.oup.com
Ambivalent effects of interleukin-6 on the pathogenesis of ischaemic stroke have been reported. However, to date, the long-term actions of interleukin-6 after stroke have not been …
K Middleton, J Jones, Z Lwin, JIG Coward - Critical reviews in oncology …, 2014 - Elsevier
During the past decade, incorporating anti-angiogenic agents into the therapeutic management of a myriad of malignancies has in certain cases made a significant impact on …
CC Zheng, HF Hu, P Hong, QH Zhang… - American journal of …, 2019 - ncbi.nlm.nih.gov
Abstract Integrin-linked kinase (ILK), which is an ankyrin repeat-containing serine/threonine protein kinase, interacts with integrin β1 and the β3 cytoplasmic domain and phosphorylates …
A Dakroub, SA Nasser, F Kobeissy… - Journal of Cellular …, 2021 - Wiley Online Library
Visfatin/nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine expressed predominately in visceral fat tissues. High circulating levels of visfatin/NAMPT have been …