The evolutionary meaning and basic molecular mechanisms involved in the determination of
longevity remain an unresolved problem. Currently, different theories are on offer in …

Aging is the single largest risk factor for many debilitating conditions, including heart
diseases, stroke, cancer, diabetes, and neurodegenerative disorders. Although far from …

DNA variants that modulate life span provide insight into determinants of health, disease,
and aging. Through analyses in the UM-HET3 mice of the Interventions Testing Program …

Adaptation to reduced energy production during aging is a fundamental issue for
maintaining healthspan or prolonging life span. Currently, however, the underlying …

Background Nanomaterials are widely used as pesticide adjuvants to increase pesticide
efficiency and minimize environmental pollution. But it is increasingly recognized that …

An important unanswered question in regenerative biology is to what extent regeneration is
accomplished by the reactivation of gene regulatory networks used during development …

Pharmacological therapies are promising interventions to slow down aging and reduce
multimorbidity in the elderly. Studies in animal models are the first step toward translation of …

Aging is characterized by chronic low‐grade inflammation in multiple tissues, also termed
“inflammaging”, which represents a significant risk factor for many aging‐related chronic …

Life activities are supported by the intricate metabolic network that is fueled by nutrients.
Nutritional and genetic studies in model organisms have determined that dietary restriction …

The extreme lipophilicity of essential oils (EOs) impedes the measurement of their biological
actions in an aqueous environment. We formulated oil in water type Pickering Artemisia …