Objective: To review the efficacy of chemoprophylaxis for opportunistic infections in persons
infected with human immunodeficiency virus (HIV). Data Sources: English-language articles …

Introduction: Pneumocystis pneumonia is a potentially life-threatening pulmonary infection
that occurs in immunocompromised individuals and HIV-infected patients with a low CD4 …

When little or no data directly comparing two treatments are available, investigators often
rely on indirect comparisons from studies testing the treatments against a control or placebo …

Background We evaluated the effectiveness of three treatment strategies for the prevention
of a first episode of Pneumocystis carinii pneumonia in patients infected with the human …

Background: Finding the optimal strategy forPneumocystis cariniiprophylaxis in patients with
human immunodeficiency virus infection can be problematic. Several prophylactic regimens …

Dapsone-induced hypersensitivity reactions may cause severe cutaneous adverse
reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS). It has …

Pneumocystis carinii remains an important pathogen for the broad spectrum of
immunocompromised individuals, despite significant advances in antimicrobial therapy. The …

Dapsone, with or without trimethoprim or pyrimethamine, has strong anti-Pneumocystis
carinii activity, as demonstrated by in vitro methods, animal studies, and clinical trials. The …

Objective: To evaluate the efficacy and safety of two oral, intermittent drug regimens for the
simultaneous primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmosis in …

Introduction Towards the end of the twentieth century, significant success was achieved in
reducing incidence in several global HIV epidemics through ongoing prevention strategies …