Dynamic DNA methylation in the brain: a new epigenetic mark for experience-dependent plasticity
Experience-dependent plasticity is the ability of brain circuits to undergo molecular,
structural and functional changes as a function of neural activity. Neural activity continuously …
structural and functional changes as a function of neural activity. Neural activity continuously …
GABAergic synapses: their plasticity and role in sensory cortex
TC Griffen, A Maffei - Frontiers in cellular neuroscience, 2014 - frontiersin.org
The mammalian neocortex is composed of a variety of cell types organized in a highly
interconnected circuit. GABAergic neurons account for only about 20% of cortical neurons …
interconnected circuit. GABAergic neurons account for only about 20% of cortical neurons …
Distinct laminar requirements for NMDA receptors in experience-dependent visual cortical plasticity
Primary visual cortex (V1) is the locus of numerous forms of experience-dependent plasticity.
Restricting visual stimulation to one eye at a time has revealed that many such forms of …
Restricting visual stimulation to one eye at a time has revealed that many such forms of …
Spike-based functional connectivity in cerebral cortex and hippocampus: loss of global connectivity is coupled to preservation of local connectivity during non-REM …
Behavioral states are commonly considered global phenomena with homogeneous neural
determinants. However, recent studies indicate that behavioral states modulate spiking …
determinants. However, recent studies indicate that behavioral states modulate spiking …
Running towards amblyopia recovery
G Sansevero, C Torelli, R Mazziotti, A Consorti… - Scientific Reports, 2020 - nature.com
Amblyopia is a neurodevelopmental disorder of the visual cortex arising from abnormal
visual experience early in life which is a major cause of impaired vision in infants and young …
visual experience early in life which is a major cause of impaired vision in infants and young …
[HTML][HTML] Sevoflurane reduced functional connectivity of excitatory neurons in prefrontal cortex during working memory performance of aged rats
X Xu, X Tian, G Wang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background Sevoflurane has been found to increase apoptosis and pathologic markers
associated with Alzheimer disease, provoking concern over their potential contribution to …
associated with Alzheimer disease, provoking concern over their potential contribution to …
Loss of GABAB‐mediated interhemispheric synaptic inhibition in stroke periphery
B Kokinovic, P Medini - The Journal of physiology, 2018 - Wiley Online Library
Key points Recovery from the potentially devastating consequences of stroke depends
largely upon plastic changes occurring in the lesion periphery and its inputs. In a focal …
largely upon plastic changes occurring in the lesion periphery and its inputs. In a focal …
Temporal processing in the visual cortex of the awake and anesthetized rat
The activity pattern and temporal dynamics within and between neuron ensembles are
essential features of information processing and believed to be profoundly affected by …
essential features of information processing and believed to be profoundly affected by …
[HTML][HTML] Experience-dependent plasticity of visual cortical microcircuits
P Medini - Neuroscience, 2014 - Elsevier
The recent decade testified a tremendous increase in our knowledge on how cell-type-
specific microcircuits process sensory information in the neocortex and on how such circuitry …
specific microcircuits process sensory information in the neocortex and on how such circuitry …
Functional determinants of enhanced and depressed interareal information flow in nonrapid eye movement sleep between neuronal ensembles in rat cortex and …
Compared with wakefulness, neuronal activity during nonrapid eye movement (NREM)
sleep is characterized by a decreased ability to integrate information, but also by the …
sleep is characterized by a decreased ability to integrate information, but also by the …