Proteins are major building blocks of life. The protein content of a cell and an organism
provides key information for the understanding of biological processes and disease. Despite …

Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Single-cell profiling methods have had a profound impact on the understanding of cellular
heterogeneity. While genomes and transcriptomes can be explored at the single-cell level …

A high throughput single-molecule method for identifying peptides and sequencing proteins
based on nanopores could reduce costs and increase speeds of sequencing, allow the …

The identification and quantification of proteins lags behind DNA-sequencing methods in
scale, sensitivity, and dynamic range. Here, we show that sparse amino acid–sequence …

While DNA sequencing is now amply available, fast, and inexpensive, protein sequencing
remains a tremendous challenge. Nanopores may allow for developing a protein sequencer …

Despite tremendous gains over the past decade, methods for characterizing proteins have
generally lagged behind those for nucleic acids, which are characterized by extremely high …

Proteomic analysis can be a critical bottleneck in cellular characterization. The current
paradigm relies primarily on mass spectrometry of peptides and affinity reagents (ie …

Proteins have been considered key building blocks of life. In particular, the protein content of
an organism and a cell offers significant information for the in-depth understanding of the …

2017-06-07 Assigned to BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM
reassignment BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM ASSIGNMENT …