Impact of reactive species on amino acids—biological relevance in proteins and induced pathologies

CMC Andrés, JM Pérez de la Lastra… - International Journal of …, 2022 - mdpi.com
This review examines the impact of reactive species RS (of oxygen ROS, nitrogen RNS and
halogens RHS) on various amino acids, analyzed from a reactive point of view of how during …

Detection of early disease risk factors associated with metabolic syndrome: a new era with the NMR metabolomics assessment

J Hernandez-Baixauli, S Quesada-Vázquez… - Nutrients, 2020 - mdpi.com
The metabolic syndrome is a multifactorial disease developed due to accumulation and
chronification of several risk factors associated with disrupted metabolism. The early …

Electronic cigarette exposure causes vascular endothelial dysfunction due to NADPH oxidase activation and eNOS uncoupling

MA El-Mahdy, MG Ewees, MS Eid… - American Journal …, 2022 - journals.physiology.org
We recently reported a mouse model of chronic electronic cigarette (e-cig) exposure-
induced cardiovascular pathology, where long-term exposure to e-cig vape (ECV) induces …

Bioactivity Potential of Prunus spinosa L. Flower Extracts: Phytochemical Profiling, Cellular Safety, Pro-inflammatory Enzymes Inhibition and Protective Effects Against Oxidative …

A Marchelak, A Owczarek, M Matczak… - Frontiers in …, 2017 - frontiersin.org
Flower extracts of Prunus spinosa L.(blackthorn)—a traditional medicinal plant of Central
and Eastern Europe indicated for the treatment of urinary tract disorders, inflammation, and …

New strategies for the total/partial replacement of conventional sodium nitrite in meat products: A review

M Stoica, VM Antohi, P Alexe, AS Ivan… - Food and Bioprocess …, 2022 - Springer
Sodium nitrite (NaNO 2) is a multifunctional meat-curing ingredient responsible for the
unique reddish-pink color and flavor, microbiological safety, and shelf life extension of …

Molecular mechanisms linking inflammation to autoimmunity in Sjögren's syndrome: Identification of new targets

M Sisto, D Ribatti, S Lisi - International Journal of Molecular Sciences, 2022 - mdpi.com
Sjögren's syndrome (SS) is a systemic autoimmune rheumatic disorder characterized by the
lymphocytic infiltration of exocrine glands and the production of autoantibodies to self …

Melatonin, its metabolites and their interference with reactive nitrogen compounds

R Hardeland - Molecules, 2021 - mdpi.com
Melatonin and several of its metabolites are interfering with reactive nitrogen. With the notion
of prevailing melatonin formation in tissues that exceeds by far the quantities in blood …

Gut microbiota metabolites as integral mediators in cardiovascular diseases

Y Zhu, X Shui, Z Liang, Z Huang… - International …, 2020 - spandidos-publications.com
Cardiovascular diseases (CVDs), such as atherosclerosis, hypertension, myocardial
infarction and diabetic heart disease, are associated with high morbidity and mortality rates …

The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells

C Campanella, A D'Anneo, AM Gammazza… - …, 2015 - pmc.ncbi.nlm.nih.gov
HSP60 undergoes changes in quantity and distribution in some types of tumors suggesting
a participation of the chaperonin in the mechanism of transformation and cancer …

Reactive nitrogen species (RNS)-resistant microbes: adaptation and medical implications

S Tharmalingam, A Alhasawi, VP Appanna… - Biological …, 2017 - degruyter.com
Nitrosative stress results from an increase in reactive nitrogen species (RNS) within the cell.
Though the RNS–nitric oxide (· NO) and peroxynitrite (ONOO−)–play pivotal physiological …