Schistosome immunomodulators
Schistosomes are long lived, intravascular parasitic platyhelminths that infect> 200 million
people globally. The molecular mechanisms used by these blood flukes to dampen host …
people globally. The molecular mechanisms used by these blood flukes to dampen host …
Microbial βγ-crystallins
A Mishra, B Krishnan, SS Srivastava… - Progress in biophysics and …, 2014 - Elsevier
Abstract βγ-Crystallins have emerged as a superfamily of structurally homologous proteins
with representatives across the domains of life. A major portion of this superfamily is …
with representatives across the domains of life. A major portion of this superfamily is …
Proteomic Identification of IPSE/alpha-1 as a Major Hepatotoxin Secreted by Schistosoma mansoni Eggs
MH Abdulla, KC Lim, JH McKerrow… - PLoS neglected tropical …, 2011 - journals.plos.org
Background Eggs deposited in the liver of the mammalian host by the blood fluke parasite,
Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response …
Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response …
A crystallin fold in the interleukin-4-inducing principle of Schistosoma mansoni eggs (IPSE/α-1) mediates IgE binding for antigen-independent basophil activation
NH Meyer, H Mayerhofer, K Tripsianes… - Journal of Biological …, 2015 - ASBMB
The IL-4-inducing principle from Schistosoma mansoni eggs (IPSE/α-1), the major secretory
product of eggs from the parasitic worm S. mansoni, efficiently triggers basophils to release …
product of eggs from the parasitic worm S. mansoni, efficiently triggers basophils to release …
Interleukin-4-Inducing Principle from Schistosoma mansoni Eggs Contains a Functional C-Terminal Nuclear Localization Signal Necessary for Nuclear Translocation …
I Kaur, G Schramm, B Everts, T Scholzen… - Infection and …, 2011 - Am Soc Microbiol
Interleukin-4-inducing principle from schistosome eggs (IPSE/alpha-1) is a protein produced
exclusively by the eggs of the trematode Schistosoma mansoni. IPSE/alpha-1 is a secretory …
exclusively by the eggs of the trematode Schistosoma mansoni. IPSE/alpha-1 is a secretory …
A shift to Th2 immune response caused by constitutive expression of IPSE/alpha-1 in transfected pig fibroblasts in mice
S Li, W Ren, W Li, N Zhao, G Ma, P Gong, Q Han… - Veterinary immunology …, 2013 - Elsevier
The IPSE/alpha-1 gene (IL-4-inducing principle of Schistosoma mansoni eggs) is a major
secreted glycoprotein of S. mansoni eggs that has a potent IL-4-inducing effect. To test the …
secreted glycoprotein of S. mansoni eggs that has a potent IL-4-inducing effect. To test the …
1H, 13C and 15N chemical shift assignments of IPSEΔNLS
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) is a
major immunogenic component of schistosomes. It potently triggers the release of …
major immunogenic component of schistosomes. It potently triggers the release of …
[PDF][PDF] Supplemental Information-Divalent cations and the divergence of βγ-crystallin function.
Table S1: Mean amino acid composition of cation-binding βγ-, lens γA-D, and lens γS-
crystallins γA-D γS βγ A 2.0±0.7 4.1±0.9 5.3±3.0 C 4.3±0.9 3.7±0.4 0.5±0.9 D 6.8±0.9 …
crystallins γA-D γS βγ A 2.0±0.7 4.1±0.9 5.3±3.0 C 4.3±0.9 3.7±0.4 0.5±0.9 D 6.8±0.9 …
[PDF][PDF] Interleukin-4 Inducing Principle from Schistosoma mansoni Eggs (IPSE/alpha-1) contains a 3 functional C-terminal nuclear localization signal necessary for …
DM Heery, FH Falcone - 2011 - Citeseer
Interleukin-4 inducing principle from schistosome eggs (IPSE/alpha-1) is a protein produced
exclusively 33 by the eggs of the trematode Schistosoma mansoni. IPSE/alpha-1 is a …
exclusively 33 by the eggs of the trematode Schistosoma mansoni. IPSE/alpha-1 is a …