Therapeutic applications of contact lens-based drug delivery systems in ophthalmic diseases

L Zhao, J Song, Y Du, C Ren, B Guo, H Bi - Drug Delivery, 2023 - Taylor & Francis
Traditional ophthalmic drugs, such as eye drops, gels and ointments, are accompanied by
many problems, including low bioavailability and potential drug side effects. Innovative …

Staphylococcus aureus and Pseudomonas aeruginosa infectious keratitis: key bacterial mechanisms that mediate pathogenesis and emerging therapeutics

S Shah, RAF Wozniak - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Bacterial keratitis (bacterial infection of the cornea) is a major cause of vision loss
worldwide. Given the rapid and aggressive nature of the disease, immediate broad …

Factors associated with 1-year outcomes and transient intraocular pressure elevation in minimally invasive glaucoma surgery using Kahook Dual Blades

T Sakamoto, H Nisiwaki - Scientific Reports, 2023 - nature.com
In this retrospective case–control study, we aimed to investigate the mid-to long-term
outcomes and factors involved in minimally invasive glaucoma surgery using the Kahook …

Yes-associated protein-1 overexpression in ocular surface squamous neoplasia; a potential diagnostic marker and therapeutic target

P Julius, SN Siyumbwa, F Maate, P Moonga… - Frontiers in …, 2023 - frontiersin.org
Yes-associated protein-1 (YAP-1) is a Hippo system transcription factor, which serves as an
oncogene in squamous cell carcinoma, and several solid tumors when the Hippo pathway is …

A proposed model of xeno-keratoplasty using 3D printing and decellularization

X Wang, RT Elbahrawi, AM Abdukadir, ZM Ali… - Frontiers in …, 2023 - frontiersin.org
Corneal opacity is a leading cause of vision impairment and suffering worldwide.
Transplantation can effectively restore vision and reduce chronic discomfort. However, there …

Predicting Prognosis Based on Regional Prevalence, Ulcer Morphology and Treatment Strategy in Vision-Threatening Pythium insidiosum Keratitis

B Gurnani, K Kaur - Clinical Ophthalmology, 2023 - Taylor & Francis
Pythium insidiosum is an oomycete belonging to the phylum Straminipila and family
Pythiaceae. It causes rapidly progressive vision-threatening keratitis. Clinically …

Meta-analysis of corneal endothelial changes after phacoemulsification in diabetic and non-diabetic patients

Y Yang, H Chai, Z Ding, C Tang, Y Liang, Y Li… - BMC …, 2023 - Springer
Background Currently, there is still controversy about the differential changes in corneal
endothelium function and morphology after phacoemulsification between Diabetes Mellitus …

Risk factors for Descemet membrane endothelial keratoplasty rejection: current perspectives-systematic review

B Gurnani, K Kaur, VG Lalgudi… - Clinical Ophthalmology, 2023 - Taylor & Francis
Descemet membrane endothelial keratoplasty (DMEK) is a corneal endothelial
transplantation procedure with selective removal of a patient's defective Descemet …

GC-MS analysis of methadone and EDDP in addicted patients under methadone substitution treatment: comparison of urine and plasma as biological samples

DM Ciucă Anghel, AM Ciobanu, CM Guțu, M Stan… - Molecules, 2022 - mdpi.com
(1) Background: Methadone, along with buprenorphine, is the most commonly used drug for
the treatment of opioid dependence. This study aimed to analyze methadone and its major …

Application of convergent science and technology toward ocular disease treatment

A Bal-Öztürk, E Özcan-Bülbül, HE Gültekin, B Cecen… - Pharmaceuticals, 2023 - mdpi.com
Eyes are one of the main critical organs of the body that provide our brain with the most
information about the surrounding environment. Disturbance in the activity of this …