The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

Ribosomal S6 kinase (RSK) family is a group of serine/threonine kinases, including four
isoforms (RSK1/2/3/4). As a downstream effector of the Ras-mitogen-activated protein …

BACKGROUND: Vein graft failure following cardiovascular bypass surgery results in
significant patient morbidity and cost to the healthcare system. Vein graft injury can occur …

High mortality of prostate cancer patients is primarily due to metastasis. Understanding the
mechanisms controlling metastatic processes remains essential to develop novel therapies …

The 90 kDa ribosomal S6 kinase (RSK) family of proteins is a group of highly conserved
Ser/Thr kinases. They are downstream effectors of the Ras/ERK/MAPK signaling cascade …

Abstract Background Rho GTPase activating protein 9 (ARHGAP9) is expressed in various
types of cancers and can inactivate Rho GTPases that mainly regulate cytoskeletal …

Rho GTPases are regulators of the actin cytoskeleton and their activity is modulated by
GTPase-activating proteins (GAPs) and guanine nucleotide exchanging factors (GEFs) …

Background: Vein graft failure (VGF) following cardiovascular bypass surgery results in
significant patient morbidity and cost to the healthcare system. Vein graft injury can occur …

Hepatic gluconeogenesis plays a crucial role in maintaining glucose homeostasis and
serves as a potential therapeutic target for type 2 diabetes, while its underlying mechanisms …

Glucagon antagonism has been reported as a new therapeutic approach to hyperglycaemia.
As the 14‐3‐3 protein YWHAB has been identified as a regulator of the glucagon receptor …