Construction of a novel in vitro atherosclerotic model from geometry‐tunable artery equivalents engineered via in‐bath coaxial cell printing

G Gao, W Park, BS Kim, M Ahn, S Chae… - Advanced Functional …, 2021 - Wiley Online Library
As the main precursor of cardiovascular diseases, atherosclerosis is a complex inflammatory
disorder that preferentially occurs in stenotic, curved, and branched arterial regions …

Recent Progress in in vitro Models for Atherosclerosis Studies

J Chen, X Zhang, R Millican, T Lynd… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is the primary cause of hardening and narrowing arteries, leading to
cardiovascular disease accounting for the high mortality in the United States. For developing …

Tissue-specific parameters for the design of ECM-mimetic biomaterials

OR Tonti, H Larson, SN Lipp, CM Luetkemeyer… - Acta biomaterialia, 2021 - Elsevier
The extracellular matrix (ECM) is a complex network of biomolecules that mechanically and
biochemically directs cell behavior and is crucial for maintaining tissue function and health …

Delivering mechanical stimulation to cells: state of the art in materials and devices design

Y Zhang, P Habibovic - Advanced Materials, 2022 - Wiley Online Library
Biochemical signals, such as growth factors, cytokines, and transcription factors are known
to play a crucial role in regulating a variety of cellular activities as well as maintaining the …

Stretchable device for simultaneous measurements of contractility and electrophysiology of neuromuscular tissue in the gastrointestinal tract

P Oldroyd, S Oldroyd, M Meng, R Makwana… - Advanced …, 2024 - Wiley Online Library
Devices interfacing with biological tissues can provide valuable insights into function,
disease, and metabolism through electrical and mechanical signals. However, certain …

[HTML][HTML] In vitro fluidic systems: Applying shear stress on endothelial cells

F Meng, H Cheng, J Qian, X Dai, Y Huang… - Medicine in Novel …, 2022 - Elsevier
Endothelial cells (ECs) that reside on the surface of blood vessels are constantly exposed to
mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple …

Extracellular matrix: paving the way to the newest trends in atherosclerosis

C Gialeli, A Shami, I Gonçalves - Current opinion in lipidology, 2021 - journals.lww.com
Extracellular matrix: paving the way to the newest trends in... : Current Opinion in Lipidology
Extracellular matrix: paving the way to the newest trends in atherosclerosis : Current Opinion …

Mechanisms of abdominal aortic aneurysm progression: A review

JP Gao, W Guo - Vascular Medicine, 2022 - journals.sagepub.com
Abdominal aortic aneurysm (AAA) is a common disease associated with significant
cardiovascular morbidity and mortality. Up to now, there is still controversy on the choice of …

Atherosclerosis and endothelial mechanotransduction: current knowledge and models for future research

M Hamrangsekachaee, K Wen… - … of Physiology-Cell …, 2023 - journals.physiology.org
Endothelium health is essential to the regulation of physiological vascular functions.
Because of the critical capability of endothelial cells (ECs) to sense and transduce chemical …

Fluid-structure interaction study of hemodynamics and its biomechanical influence on carotid artery atherosclerotic plaque deposits

AJ Oyejide, AA Awonusi, EO Ige - Medical Engineering & Physics, 2023 - Elsevier
Atherosclerotic plaque deposits are common causes of blood flow disruption in the carotid
artery bifurcation and the associated fluid mechanics has been extensively studied using …