Since the 1980s, we have witnessed the rapid development of genetically modified mouse
models of human diseases. A large number of transgenic and knockout mice have been …

IntelliCage for mice is a rodent home-cage equipped with four corner structures harboring
symmetrical double panels for operant conditioning at each of the two sides, either by …

Ceftriaxone (CEF) is a safe and multipotent antimicrobial agent that possesses
neuroprotective properties. Earlier, we revealed the restoration of cognitive function in OXYS …

The use of animal models for substance use disorder (SUD) has made an important
contribution in the investigation of the behavioral and molecular mechanisms underlying …

Introduction The four members of the p90 ribosomal S6 kinase (RSK) family are
serine/threonine protein kinases, which are phosphorylated and activated by ERK1/2 …

Genome wide association meta-analysis identified ST3GAL3, a gene encoding the beta-
galactosidase-alpha-2, 3-sialyltransferase-III, as a risk gene for attention-deficit/hyperactivity …

Fluoxetine is a clinically successful antidepressant. It is a racemic mixture of (R) and (S)
stereoisomers. In preclinical studies, chronic treatment with fluoxetine (10 mg/kg) had …

Adult neurogenesis is involved in certain hippocampus-dependent cognitive functions and is
linked to psychiatric diseases including intellectual disabilities. The Coffin-Lowry syndrome …

The failure of animal studies to translate to effective clinical therapeutics has driven efforts to
identify underlying cause and develop solutions that improve the reproducibility and …

Intellectual disability (ID) is a neurodevelopmental disorder associated with impaired
cognitive and adaptive behaviors and represents a major medical issue. Although ID …