Decoding the role of miRNAs in multiple myeloma pathogenesis: a focus on signaling pathways

AM Yehia, EGE Elsakka, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a cancer of plasma cells that has been extensively studied in
recent years, with researchers increasingly focusing on the role of microRNAs (miRNAs) in …

MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

N Amodio, L Raimondi, G Juli, MA Stamato… - Journal of hematology & …, 2018 - Springer
The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …

Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+ γδ1 Treg cells

C Ni, QQ Fang, WZ Chen, JX Jiang, Z Jiang… - Signal transduction and …, 2020 - nature.com
Abstract γδT cells have been reported to exert immunosuppressive functions in multiple
solid malignant diseases, but their immunosuppressive functional subpopulation in breast …

[HTML][HTML] Focus: Epigenetics: The role of the ubiquitously expressed transcription factor Sp1 in tissue-specific transcriptional regulation and in disease

L O'Connor, J Gilmour, C Bonifer - The Yale journal of biology and …, 2016 - ncbi.nlm.nih.gov
Sp1 belongs to the 26 member strong Sp/KLF family of transcription factors. It is a paradigm
for a ubiquitously expressed transcription factor and is involved in regulating the expression …

MicroRNA networks modulate oxidative stress in cancer

YH Lin - International journal of molecular sciences, 2019 - mdpi.com
Imbalanced regulation of reactive oxygen species (ROS) and antioxidant factors in cells is
known as “oxidative stress (OS)”. OS regulates key cellular physiological responses through …

Crosstalk between noncoding RNAs and ferroptosis: new dawn for overcoming cancer progression

X Zhang, L Wang, H Li, L Zhang, X Zheng… - Cell Death & …, 2020 - nature.com
Cancer progression including proliferation, metastasis, and chemoresistance has become a
serious hindrance to cancer therapy. This phenomenon mainly derives from the innate …

Reprogramming of amino acid transporters to support aspartate and glutamate dependency sustains endocrine resistance in breast cancer

M Bacci, N Lorito, L Ippolito, M Ramazzotti, S Luti… - Cell reports, 2019 - cell.com
Endocrine therapy (ET) is the standard of care for estrogen receptor-positive (ER+) breast
cancers. Despite its efficacy,∼ 40% of women relapse with ET-resistant (ETR) disease. A …

The role and function of microRNA in the pathogenesis of multiple myeloma

H Handa, Y Murakami, R Ishihara, K Kimura-Masuda… - Cancers, 2019 - mdpi.com
Recently, attention has been drawn to the role of non-coding regions of the genome in
cancer pathogenesis. MicroRNAs (miRNAs) are small non-coding RNAs with 19–25 bases …

Controlling the immune suppressor: transcription factors and microRNAs regulating CD73/NT5E

T Kordaß, W Osen, SB Eichmüller - Frontiers in immunology, 2018 - frontiersin.org
The NT5E (CD73) molecule represents an ecto-5′-nucleotidase expressed on the cell
surface of various cell types. Hydrolyzing extracellular adenosine monophosphate into …

[PDF][PDF] RETRACTED ARTICLE: Long non-coding RNA CCAT1 promotes multiple myeloma progression by acting as a molecular sponge of miR-181a-5p to modulate …

L Chen, N Hu, C Wang, H Zhao, Y Gu - Cell Cycle, 2018 - Taylor & Francis
Statement of Retraction We, the Editors and Publisher of the journal Cell Cycle, have
retracted the following article: Li Chen, Ning Hu, Chao Wang, Hongmian Zhao and Yueli Gu …