The tripartite subdivision of lymphocytes into B cells, αβ T cells, and γδ cells has been
conserved seemingly since the emergence of jawed vertebrates, more than 450 million …

While most T cells use a CD3-associated α/β T cell receptor as antigen recognition structure,
a second population of T cells expresses the alternative γ/δ T cell receptor. γ/δ T cells are a …

T LYMPHOCYTES express either αβ or γδ T-cell receptor heterodimers1, 2. Most αβ T cells
recognize antigenic peptides bound to major histocompatibility complex molecules but the …

T cells bearing γδ T cell antigen receptors (TCRs) function in lymphoid stress surveillance.
However, the contribution of γδ TCRs to such responses is unclear. Here we found that the …

Abstract Vγ9Vδ2 T lymphocytes, a major γδ T lymphocyte subset in humans, display cytolytic
activity against various tumor cells upon recognition of yet uncharacterized structures. Here …

The mechanisms involved in host clearance of symptomatic mucocutaneous herpes simplex
virus (HSV) infection are unclear. We studied the functional properties of bulk cultures of skin …

▪ Abstract In contrast with the study of αβ T cells, that of γδ T cells is relatively recent and
stems from the discovery of their rearranged genes, rather than from any knowledge of their …

Influenza vaccines that induce greater cross-reactive or heterosubtypic immunity (Het-I) may
overcome limitations in vaccine efficacy imposed by the antigenic variability of influenza A …

Recent reports have demonstrated immune activation in dengue hemorrhagic fever (DHF)
by cytokine and soluble receptor detection in blood. The goal of this study was to determine …

γδ T cells are much less common than αβ T cells, accounting for 0.5% to 5% of all T
lymphocytes in the peripheral blood and lymphoid tissues in mice and humans. However …