Schizophrenia (SZ) is a mental disorder that typically emerges in late adolescence or early
adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior …

After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …

“Is there a biology of intelligence which is characteristic of the normal human nervous
system?” Here we review 37 modern neuroimaging studies in an attempt to address this …

The prefrontal cortex (PFC) regulates emotional responses, but it is unclear how PFC
integrates diverse inputs to select the appropriate response. We therefore evaluated the …

Brain-imaging studies suggest that antisocial and violent behavior is associated with
structural and functional deficits in the prefrontal cortex, but there is heterogeneity in findings …

The insula is anatomically situated to be critically involved in many bio-behavioral functions
impaired in schizophrenia. Furthermore, its total volume has been shown to be reduced in …

OBJECTIVE: Voxel-based morphometry is a method for detecting group differences in the
density or volume of brain matter. The authors reviewed the literature on use of voxel-based …

David A. Lewis*‡ and Jeffrey A. Lieberman†‡* Departments of Psychiatry and Neuroscience
University of Pittsburgh School of Medicine this syndrome is increased as well. Recently …

Background Glial cells are more numerous than neurons in the cortex and are crucial to
neuronal function. There is evidence for reduced neuronal size in schizophrenia, with …

The authors review existing structural and functional neuroimaging studies of patients with
bipolar disorder and discuss how these investigations enhance our understanding of the …