Cutaneous wound healing is the process by which skin repairs itself. It is generally accepted
that cutaneous wound healing can be divided into 4 phases: haemostasis, inflammation …

Shikonin is the major bioactive component extracted from the roots of Lithospermum
erythrorhizon which is also known as “Zicao” in Traditional Chinese Medicine (TCM). Recent …

Background Shikonin is one of the major phytochemical components of Lithospermum
erythrorhizon (Purple Cromwell), which is a type of medicinal herb broadly utilized in …

Hypertrophic scars are unfavorable skin diseases characterized by excessive collagen
deposition. Although systemic treatments exist in clinic to manage hypertrophic scars, they …

Shikonin is a natural compound isolated from herbs and traditional medicines that have
been used in a number of countries to treat various illnesses including inflammation, virus …

Currently, skin injuries have a serious impact on people's lives and socio-economic stress.
Shikonin, a naphthoquinone compound derived from the root of the traditional Chinese …

Background: Mechanical ventilation (MV) can induce pulmonary fibrosis. This study aims to
investigate whether MV-induced pulmonary fibrosis is associated with aerobic glycolysis …

Shikonin, an active ingredient of Lithospermum erythrorhizon, exerts anti-inflammatory and
antibacterial effects, and promotes wound healing. We investigated whether shikonin …

A diabetic ulcer (DU) is a dreaded and resistant complication of diabetes mellitus with high
morbidity. Fu-Huang ointment (FH ointment) is a proven recipe for treating chronic refractory …

Scars are common complications of burns and trauma, resulting in mental trauma, physical
pain, and a heavy financial burden for patients. Specific and effective anti‐scarring drugs are …