Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

The glycosides of two flavonoids, naringin and naringenin, are found in various citrus fruits,
bergamots, tomatoes, and other fruits. These phytochemicals are associated with multiple …

As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …

According to epidemiological research, as the population ages, neurological illnesses are
becoming a bigger issue. Despite improvements in the treatment of these diseases, there …

Microglia are resident immune cells in the central nervous system and play critical roles in
brain immunity, development, and homeostasis. The pathology of Alzheimer's disease (AD) …

Although different regions of the brain are dedicated to specific functions, the intra-and inter-
regional heterogeneity of astrocytes and microglia in these regions has not yet been fully …

The present study examines functional contributions of microglia in host defense,
demyelination, and remyelination following infection of susceptible mice with a neurotropic …

Stroke is one of the leading causes of death worldwide and currently only few therapeutic
options are available. Stroke is a sexually dimorphic disease contributing to the difficulty in …

Neuroinflammation, characterized by a complex interplay among innate and adaptive
immune responses within the central nervous system (CNS), is crucial in responding to …

Neurodegenerative polyglutamine (polyQ) disorders are caused by trinucleotide repeat
expansions within the coding region of disease-causing genes. PolyQ-expanded proteins …