Therapeutic options targeting oxidative stress, mitochondrial dysfunction and inflammation to hinder the progression of vascular complications of diabetes
Type 2 diabetes mellitus is a leading cause of morbidity and mortality worldwide, given its
serious associated complications. Despite constant efforts and intensive research, an …
serious associated complications. Despite constant efforts and intensive research, an …
Emerging therapeutic options in the management of diabetes: recent trends, challenges and future directions
Diabetes is a serious health issue that causes a progressive dysregulation of carbohydrate
metabolism due to insufficient insulin hormone, leading to consistently high blood glucose …
metabolism due to insufficient insulin hormone, leading to consistently high blood glucose …
Milestones in the journey towards addressing obesity; Past trials and triumphs, recent breakthroughs, and an exciting future in the era of emerging effective medical …
The 21st century is characterized by an increasing incidence and prevalence of obesity and
the burden of its associated comorbidities, especially cardiometabolic diseases, which are …
the burden of its associated comorbidities, especially cardiometabolic diseases, which are …
Repurposing drugs targeting metabolic diseases for cancer therapeutics
Highlights•Discovery of new drugs against cancer is of utmost importance.•Drug repurposing
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …
is an alternative approach to traditional drug discovery.•It significantly reduces the R&D …
[HTML][HTML] Hempseed (Cannabis sativa) protein hydrolysates: A valuable source of bioactive peptides with pleiotropic health-promoting effects
G Santos-Sánchez, AI Álvarez-López… - Trends in Food Science …, 2022 - Elsevier
Background Recently, the study of hydrolysates from food proteins has been increasingly
due to their wide range of biological activities. Hydrolysates contain peptides of 2–20 amino …
due to their wide range of biological activities. Hydrolysates contain peptides of 2–20 amino …
Antidiabetic treatment with gliptins: focus on cardiovascular effects and outcomes
EZ Fisman, A Tenenbaum - Cardiovascular diabetology, 2015 - Springer
The traditional oral pharmacological therapy for type 2 diabetes mellitus (T2DM) has been
based on the prescription of metformin, a biguanide, as first line antihyperglycemic agent …
based on the prescription of metformin, a biguanide, as first line antihyperglycemic agent …
Minimizing glycemic fluctuations in patients with type 2 diabetes: approaches and importance
P Dandona - Diabetes technology & therapeutics, 2017 - liebertpub.com
Glycemic fluctuations, characterized by short-term oscillations in plasma glucose, are
important when managing type 2 diabetes (T2D) and may be considered a target of glucose …
important when managing type 2 diabetes (T2D) and may be considered a target of glucose …
Anti-hyperglycaemic activity of H. rosa-sinensis leaves is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of insulin secretion
Ethnopharmacological relevance Hibiscus rosa-sinensis (HRS) is a tropical flowery plant,
widely distributed in Asian region and an important traditional medicine used in many …
widely distributed in Asian region and an important traditional medicine used in many …
[HTML][HTML] Solvation effects, structural, vibrational analysis, chemical reactivity, nanocages, ELF, LOL, docking and MD simulation on Sitagliptin
Sitagliptin is a medication used to manage type-2 diabetes. The present study investigates
the experimental and theoretical results of Sitagliptin (SG). Density functional theory (DFT) …
the experimental and theoretical results of Sitagliptin (SG). Density functional theory (DFT) …
New bioactive peptides identified from a tilapia byproduct hydrolysate exerting effects on DPP-IV activity and intestinal hormones regulation after canine …
S Theysgeur, B Cudennec, B Deracinois, C Perrin… - Molecules, 2020 - mdpi.com
Like their owners, dogs and cats are more and more affected by overweight and obesity-
related problems and interest in functional pet foods is growing sharply. Through numerous …
related problems and interest in functional pet foods is growing sharply. Through numerous …