Abstract An estimated 500,000 to 600,000 bone grafting procedures are done annually in
the United States. Approximately ½ of these surgeries involve spinal arthrodesis whereas …

Optimal bone graft substances generally possess one or more of three essential
elements:(1) osteoinductive factors that induce the various stages of bone regeneration,(2) …

In a prospective, nonrandomized, multicenter study, 109 patients with bone defects were
treated with a surgical grade calcium sulfate preparation as a bone graft substitute. The …

Calcium sulfate, plaster of Paris, has a long clinical history for use as a bone graft substitute
in various skeletal sites. The current authors examined the in vivo response of calcium …

Calcium sulfate was used as a biodegradable delivery system for the administration of
antibiotics in musculoskeletal infection. New Zealand white rabbits were infected with …

Methods Graft materials: The grafts consisted of either circular 4.7 3-mm tablets of calcium
sulfate dihydrate (CaSO4) or autogenous cancellous bone. Experimental model: The grafts …

Long bone defects due to nonunion or surgical excision of benign bone tumors result in
areas that require rapid regeneration of local bone. This clinical and radiographic article …

We studied the effects of a newly marketed bone substitute, Osteoset, on bone healing in a
tibial defect in humans. 20 patients undergoing an ACL (anterior cruciate ligament) …

The case of a 24-year-old woman with Pseudomonas aeruginosa and Proteus mirabilis
chronic calcaneal osteomyelitis is presented. Extensive debridement of the necrotic bone …

Allograft bone extenders are commonly used in spinal surgery to increase the available graft
volume, thereby promoting and achieving a solid fusion mass. We report a single surgeon's …