This review describes new developments in the study of transgenerational epigenetic
inheritance, a component of epigenetics. We start by examining the basic concepts of the …

Polyploids—organisms that have multiple sets of chromosomes—are common in certain
plant and animal taxa, and can be surprisingly stable. The evidence that has emerged from …

The environment experienced by an animal can sometimes influence gene expression for
one or a few subsequent generations. Here, we report the observation that a temperature …

The testis produces gametes through spermatogenesis and evolves rapidly at both the
morphological and molecular level in mammals,,,,–, probably owing to the evolutionary …

Transgenerational effects have wide-ranging implications for human health, biological
adaptation, and evolution; however, their mechanisms and biology remain poorly …

During development, cells start in a pluripotent state, from which they can differentiate into
many cell types, and progressively develop a narrower potential. Their gene-expression …

Histone methylation regulates chromatin structure, transcription, and epigenetic state of the
cell. Histone methylation is dynamically regulated by histone methylases and demethylases …

For proper development, cells must retain patterns of gene expression and repression
through cell division. Repression via methylation of histone H3 on Lys27 (H3K27me) by …

X chromosome inactivation is most commonly studied in the context of female mammalian
development, where it performs an essential role in dosage compensation. However …

Transgenerational epigenetic effects include all processes that have evolved to achieve the
nongenetic determination of phenotype. There has been a long-standing interest in this area …