Members of the genus Bacillus are known to produce a wide arsenal of antimicrobial
substances, including peptide and lipopeptide antibiotics, and bacteriocins. Many of the …

Interest in protein disulfide bond formation has recently increased because of the prominent
role of disulfide bonds in bacterial virulence and survival. The first discovered pathway that …

If DNA is the information of life, then proteins are the machines of life—but they must be
assembled and correctly folded to function. A key step in the protein-folding pathway is the …

Covering: up to July 2008 Ribosomally synthesized bacterial natural products rival the
nonribosomal peptides in their structural and functional diversity. The last decade has seen …

The identification of protein disulfide isomerase, almost 50 years ago, opened the way to the
study of oxidative protein folding. Oxidative protein folding refers to the composite process …

Bacillus subtilis has become a widely used microbial cell factory for the production of
recombinant proteins, especially those associated with foods and food processing. Recent …

Disulfide-bond formation is important for the correct folding of a great number of proteins that
are exported to the cell envelope of bacteria. Bacterial cells have evolved elaborate systems …

In oxidative folding of proteins in the bacterial periplasmic space, disulfide bonds are
introduced by the oxidation system and isomerized by the reduction system. These systems …

Abstract Background The Gram-positive bacterium Bacillus subtilis is an important producer
of high quality industrial enzymes and a few eukaryotic proteins. Most of these proteins are …

Abstract The Gram-positive bacterium Bacillus subtilis and some of its close relatives are
widely used for the industrial production of enzymes for the detergents, food, and beverage …