Chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are genetically
engineered immune cells that can detect target antigens on the surface of target cells and …

Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Background Reported urban malaria cases are increasing in Latin America, however,
evidence of such trend remains insufficient. Here, we propose an integrated approach that …

Malaria is a vector-borne disease that involves multiple parasite species in a variety of
ecological settings. However, the parasite species causing the disease, the prevalence of …

Whole genome sequencing (WGS) is increasingly used for molecular diagnosis and
epidemiology of infectious diseases. Current Leishmania genomic studies rely on DNA …

Background: Diversity in Plasmodium falciparum poses a major threat to malaria control and
elimination interventions. This study utilized 12 polymorphic microsatellite (MS) markers and …

Plasmodium falciparum and Plasmodium vivax have varying transmission dynamics that are
informed by molecular epidemiology. This study aimed to determine the complexity of …

Background Parasite genetic diversity and multiplicity of infection (MOI) affect clinical
outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity …

Introduction. The characterization of genetic profile of Plasmodium isolates from different
areas could help in better strategies for malaria elimination. This study aimed to compare P …

Plasmodium relapses are attributed to the activation of dormant liver-stage parasites and are
responsible for a significant number of recurring malaria blood-stage infections. While …