This review discusses the structure and function of molecular chaperones, with emphasis on
their role in rescuing misfolded proteins. It also includes a discussion of the diseases in …

In the eukaryotic cell an intrinsic mechanism is present providing the ability to defend itself
against external stressors from various sources. This defense mechanism probably evolved …

Ageing, a basic biological process seen in all living creatures, is not preventable. Surgical
and topical modalities have been invented and substances were applied topically to alter …

Aging and age-related disorders such as Alzheimer's disease (AD) are usually
accompanied by oxidative stress as one of the main mechanisms contributing to …

The wide range of disease prevalences reported in epidemiological studies of
temporomandibular degenerative joint disease reflects the fact that diagnoses are frequently …

Ageing is associated with a progressive decline of muscle mass, strength, and quality, a
condition known as sarcopenia. Due to the progressive ageing of western populations, age …

A decline in an organism's ability to cope with stress through acute response protein
expression may contribute to stress intolerance with aging. We investigated the influence of …

The fundamental functions of heat shock proteins (HSPs) are molecular chaperoning and
cellular repair. There is little literature on the association between the numerous functions of …

Abstract Background/Aims: Morphofunctional studies suggest that the liver, compared with
other organs, ages fairly well. Its success is ascribable to its lasting ability to regenerate …

Chaperone function plays a key role in repairing proteotoxic damage, in the maintenance of
cell architecture, and in cell survival. Here, we summarize our current knowledge about …