Asymmetric activation of the calcium-sensing receptor homodimer

Y Gao, MJ Robertson, SN Rahman, AB Seven… - Nature, 2021 - nature.com
The calcium-sensing receptor (CaSR), a cell-surface sensor for Ca2+, is the master
regulator of calcium homeostasis in humans and is the target of calcimimetic drugs for the …

Therapeutic Potential for Metabotropic Glutamate Receptor 7 Modulators in Cognitive Disorders

HH Parent, CM Niswender - Molecular Pharmacology, 2024 - ASPET
Metabotropic glutamate receptor 7 (mGlu7) is the most highly conserved and abundantly
expressed mGlu receptor in the human brain. The presynaptic localization of mGlu7 …