A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies

M Kumari, RM Lu, MC Li, JL Huang, FF Hsu… - Journal of biomedical …, 2022 - Springer
The novel coronavirus disease (COVID-19) pandemic remains a global public health crisis,
presenting a broad range of challenges. To help address some of the main problems, the …

Impact of antigenic evolution and original antigenic sin on SARS-CoV-2 immunity

M Aguilar-Bretones, RAM Fouchier… - The Journal of …, 2023 - Am Soc Clin Investig
Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
vaccinations targeting the spike protein (S) offer protective immunity against coronavirus …

Prior SARS-CoV-2 infection enhances and reshapes spike protein–specific memory induced by vaccination

V Barateau, L Peyrot, C Saade, B Pozzetto… - Science Translational …, 2023 - science.org
The diversity of vaccination modalities and infection history are both variables that have an
impact on the immune memory of individuals vaccinated against SARS-CoV-2. To gain more …

Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

WN Voss, ML Mallory, PO Byrne, JM Marchioni… - Cell Reports …, 2024 - cell.com
We describe the molecular-level composition of polyclonal immunoglobulin G (IgG) anti-
spike antibodies from ancestral severe acute respiratory syndrome coronavirus 2 (SARS …

[HTML][HTML] Dissecting the intricacies of human antibody responses to SARS-CoV-1 and SARS-CoV-2 infection

R Wang, Y Han, R Zhang, J Zhu, X Nan, Y Liu, Z Yang… - Immunity, 2023 - cell.com
The 2003 severe acute respiratory syndrome coronavirus (SARS-CoV-1) causes more
severe disease than SARS-CoV-2, which is responsible for COVID-19. However, our …

Different neutralization profiles after primary SARS-CoV-2 Omicron BA. 1 and BA. 2 infections

I Medits, DN Springer, M Graninger, JV Camp… - Frontiers in …, 2022 - frontiersin.org
Background and Methods The SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) Omicron (B. 1.1. 529) variant is the antigenically most distinct variant to date …

Attenuated humoral responses in HIV after SARS-CoV-2 vaccination linked to B cell defects and altered immune profiles

E Touizer, A Alrubayyi, R Ford, N Hussain, PP Gerber… - Iscience, 2023 - cell.com
We assessed a cohort of people living with human immunodeficiency virus (PLWH)(n= 110)
and HIV negative controls (n= 64) after 1, 2 or 3 SARS-CoV-2 vaccine doses. At all …

Relative effectiveness of COVID-19 vaccination with 3 compared to 2 doses against SARS-CoV-2 B. 1.1. 529 (Omicron) among an Australian population with low prior …

B Liu, H Gidding, S Stepien, M Cretikos, K Macartney - Vaccine, 2022 - Elsevier
Background We estimate effectiveness of 3 versus 2 vaccine doses against SARS-CoV-2 B.
1.1. 529 Omicron in a mostly infection-naiive but highly vaccinated Australian population …

Antibody‐mediated SARS‐CoV‐2 entry in cultured cells

MG Kibria, CL Lavine, W Tang, S Wang, H Gao… - EMBO …, 2023 - embopress.org
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) enters host cells by first
engaging its cellular receptor angiotensin converting enzyme 2 (ACE2) to induce …

In-silico evaluation of adenoviral COVID-19 vaccination protocols: Assessment of immunological memory up to 6 months after the third dose

P Stolfi, F Castiglione, E Mastrostefano… - Frontiers in …, 2022 - frontiersin.org
Background The immune response to adenoviral COVID-19 vaccines is affected by the
interval between doses. The optimal interval is unknown. Aim We aim to explore in-silico the …