Therapeutic perspective of vitamin C and its derivatives

A Meščić Macan, T Gazivoda Kraljević, S Raić-Malić - Antioxidants, 2019 - mdpi.com
l-Ascorbic acid (ASA), vitamin C, is a ubiquitous carbohydrate-like compound that has an
essential role in a number of cellular processes, such as collagen synthesis, cellular …

Comparison of vitamin c and its derivative antioxidant activity: Evaluated by using density functional theory

Y Liu, C Liu, J Li - ACS omega, 2020 - ACS Publications
Vitamin C (VC) is an essential antioxidant, but its application is limited because of its
unstable chemical properties. Hence, a variety of VC derivatives have emerged in practical …

The role of hyaluronan in myelination and remyelination after white matter injury

S Diao, M Xiao, C Chen - Brain Research, 2021 - Elsevier
Hyaluronan is one of the major components of the neural extracellular matrix (ECM) and
provides structural support in physiological conditions. Altered hyaluronan regulation is …

Lavandula stoechas essential oil from Spain: Aromatic profile determined by gas chromatography–mass spectrometry, antioxidant and lipoxygenase inhibitory …

A Carrasco, V Ortiz-Ruiz, R Martinez-Gutierrez… - Industrial Crops and …, 2015 - Elsevier
Lavandula stoechas essential oils (EOs), obtained from plants grown in the South East of
Spain, were analyzed by gas chromatography coupled with mass spectrometry (GC–MS) …

Lavandula angustifolia and Lavandula latifolia essential oils from Spain: Aromatic profile and bioactivities

A Carrasco, R Martinez-Gutierrez, V Tomas… - Planta …, 2016 - thieme-connect.com
Compositions of true lavender (Lavandula angustifolia) and spike lavender (Lavandula
latifolia) essential oils, cultivated and extracted in the Southeast of Spain, were determined …

Inhibition of sPLA2 enzyme activity by cell‐permeable antioxidant EUK‐8 and downregulation of p38, Akt, and p65 signals induced by sPLA2 in inflammatory mouse …

K Jayachandra, MDM Gowda… - Journal of Cellular …, 2023 - Wiley Online Library
The arachidonic acid (AA) metabolic pathway, plays a vital role in the production of
eicosanoids by the action of pro‐inflammatory secretory phospholipase A2 (PLA2). Release …

Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A2 group IIA, 5 …

V Joshi, SH Venkatesha, C Ramakrishnan… - Pharmacological …, 2016 - Elsevier
Elevated production of arachidonic acid (AA)-derived pro-inflammatory eicosanoids due to
the concerted action of secretory phospholipase A 2 group IIA (sPLA 2 IIA), 5-lipoxygenase …

Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids

V Leláková, K Šmejkal, K Jakubczyk, O Veselý… - Food chemistry, 2019 - Elsevier
Stilbenoids represent a large group of bioactive compounds, which occur in food and
medicinal plants. Twenty-five stilbenoids were screened in vitro for their ability to inhibit COX …

Ascorbic acid 6-palmitate modulates microglia M1/M2 polarization in lipopolysaccharide-stimulated BV-2 cells via PERK/elF2α mediated endoplasmic reticulum stress

Q Li, Y Wu, X Chen, T Zeng, L Liu, Z Feng, D Liu… - … Medicine and Therapies, 2022 - Springer
Background Neuroinflammation-mediated microglia polarization is a major process in
various central nervous system (CNS) diseases. Endoplasmic reticulum (ER) stress …

Polyphenolic Profile of Callistemon viminalis Aerial Parts: Antioxidant, Anticancer and In Silico 5-LOX Inhibitory Evaluations

S Mahgoub, N Hashad, S Ali, R Ibrahim, AM Said… - Molecules, 2021 - mdpi.com
Five new compounds viz kaempferol 3-O-(4 ″-galloyl)-β-d-glucopyranosyl-(1‴→ 6 ″)-O-β-
d-glucopyranoside (1), kaempferol 3-O-β-d-mannuronopyranoside (2), kaempferol 3-O-β-d …