Autoimmunity in rheumatoid arthritis: citrulline immunity and beyond

L Klareskog, K Lundberg, V Malmström - Advances in immunology, 2013 - Elsevier
Rheumatoid arthritis (RA) represents a disease where we have recently acquired new
knowledge on etiology and molecular pathogenesis, by combining data from studies on …

Occupational exposure to textile dust increases the risk of rheumatoid arthritis: results from a Malaysian population-based case–control study

CL Too, NA Muhamad, A Ilar, L Padyukov… - Annals of the …, 2016 - ard.bmj.com
Objectives Lung exposures including cigarette smoking and silica exposure are associated
with the risk of rheumatoid arthritis (RA). We investigated the association between textile …

Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian …

CL Too, A Yahya, S Murad, JS Dhaliwal… - Arthritis research & …, 2012 - Springer
Introduction Rheumatoid arthritis (RA) is a multifactorial autoimmune disease in which
genetic and environmental factors interact in the etiology. In this study, we investigated …

Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis

I Sandal, A Karydis, J Luo, A Prislovsky… - Arthritis research & …, 2016 - Springer
Background The linkage between periodontal disease and rheumatoid arthritis is well
established. Commonalities among the two are that both are chronic inflammatory diseases …

Interactions between amino acid–defined major histocompatibility complex class II variants and smoking in seropositive rheumatoid arthritis

K Kim, X Jiang, J Cui, B Lu… - Arthritis & …, 2015 - Wiley Online Library
Objective To define the interaction between cigarette smoking and HLA polymorphisms in
seropositive rheumatoid arthritis (RA), in the context of a recently identified amino acid …

A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia

H Zhao, J Xu, H Zhang, J Sun, Y Sun, Z Wang… - The American Journal of …, 2012 - cell.com
A genome-wide association study of Han Chinese subjects was conducted to identify
genetic susceptibility loci for nonobstructive azoospermia (NOA). In the discovery stage, 802 …

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis

CL Too, S Murad, JS Dhaliwal, P Larsson… - Arthritis research & …, 2012 - Springer
Introduction The majority of our knowledge regarding disease-related mechanisms of
uncontrolled citrullination and anti-citrullinated protein antibody development in rheumatoid …

Geo-epidemiology of autoantibodies in rheumatoid arthritis: comparison between four ethnically diverse populations

EC de Moel, LA Trouw, C Terao, N Govind… - Arthritis Research & …, 2023 - Springer
Background Rheumatoid arthritis (RA) occurs across the globe in different ethnic
populations. Most RA patients harbor anti-modified protein antibodies (AMPA); however, it is …

Silica exposure is associated with an increased risk of developing ACPA-positive rheumatoid arthritis in an Asian population: evidence from the Malaysian MyEIRA …

A Yahya, C Bengtsson, P Larsson, CL Too… - Modern …, 2014 - academic.oup.com
Objectives. Silica exposure has been associated with an increased risk of developing
rheumatoid arthritis (RA), especially among smokers. In this study, we aimed at examining …

Approach for identifying human leukocyte antigen (HLA)-DR bound peptides from scarce clinical samples

T Heyder, M Kohler, NK Tarasova, S Haag… - Molecular & Cellular …, 2016 - ASBMB
Immune-mediated diseases strongly associating with human leukocyte antigen (HLA)
alleles are likely linked to specific antigens. These antigens are presented to T cells in the …