Bioinspired applications of porphyrin derivatives

JM Park, KI Hong, H Lee, WD Jang - Accounts of chemical …, 2021 - ACS Publications
Conspectus Porphyrin derivatives are ubiquitous in nature and have important biological
roles, such as in light harvesting, oxygen transport, and catalysis. Owing to their intrinsic π …

Porous hydrogen-bonded organic frameworks (HOFs): From design to potential applications

J Yang, J Wang, B Hou, X Huang, T Wang… - Chemical Engineering …, 2020 - Elsevier
Abstract Hydrogen-bonded frameworks (HOFs), which are constructed from organic moieties
via hydrogen bonding, represent an emerging attractive class of porous crystalline materials …

SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways

I Batinic-Haberle, A Tovmasyan… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Superoxide dismutase (SOD) enzymes are indispensable and ubiquitous
antioxidant defenses maintaining the steady-state levels of O2·−; no wonder, thus, that their …

Mn porphyrin-based redox-active drugs: differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury

I Batinic-Haberle, A Tovmasyan… - Antioxidants & Redox …, 2018 - liebertpub.com
Significance: After approximatelty three decades of research, two Mn (III) porphyrins (MnPs),
MnTE-2-PyP5+ (BMX-010, AEOL10113) and MnTnBuOE-2-PyP5+ (BMX-001), have …

[HTML][HTML] An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins–from superoxide dismutation to H2O2-driven pathways

I Batinic-Haberle, A Tovmasyan, I Spasojevic - Redox biology, 2015 - Elsevier
Most of the SOD mimics thus far developed belong to the classes of Mn-(MnPs) and Fe
porphyrins (FePs), Mn (III) salens, Mn (II) cyclic polyamines and metal salts. Due to their …

[HTML][HTML] Nanostructured binuclear Fe (III) and Mn (III) porphyrin materials: Tuning the mimics of catalase and peroxidase activity

MBMS Martins, GA Corrêa, T Moniz, CJ Medforth… - Journal of …, 2023 - Elsevier
Tuning of the structures and electronic effects of nanocrystals is of great relevance to the
preparation of specialized materials such as artificial enzymes. In this study, binary …

A dynamic 3d hydrogen‐bonded organic frameworks with highly water affinity

YH Luo, XT He, DL Hong, C Chen… - Advanced Functional …, 2018 - Wiley Online Library
Owing to the critical roles it plays for both structure and functionality, hydrogen bonding has
high hopes for the orientated applications in hydrogen‐bonded organic frameworks (HOFs) …

[HTML][HTML] Advances on antimicrobial photodynamic inactivation mediated by Zn (II) porphyrins

THS Souza, JF Sarmento-Neto, SO Souza… - … of Photochemistry and …, 2021 - Elsevier
Over the years, microorganisms have developed several resistance mechanisms against
standard treatments, thus limiting the effect of drugs and rendering ineffective therapies …

H2O2‐Driven Anticancer Activity of Mn Porphyrins and the Underlying Molecular Pathways

I Batinic-Haberle, A Tovmasyan… - Oxidative medicine …, 2021 - Wiley Online Library
Mn (III) ortho‐N‐alkyl‐and N‐alkoxyalkyl porphyrins (MnPs) were initially developed as
superoxide dismutase (SOD) mimics. These compounds were later shown to react with …

[HTML][HTML] Thiol regulation by Mn porphyrins, commonly known as SOD mimics

I Batinic-Haberle, ME Tome - Redox biology, 2019 - Elsevier
Superoxide dismutases play an important role in human health and disease. Three decades
of effort have gone into synthesizing SOD mimics for clinical use. The result is the Mn …