Bridging bio–nano science and cancer nanomedicine

M Bjornmalm, KJ Thurecht, M Michael, AM Scott… - ACS …, 2017 - ACS Publications
The interface of bio–nano science and cancer medicine is an area experiencing much
progress but also beset with controversy. Core concepts of the field eg, the enhanced …

Mathematical modeling in cancer nanomedicine: a review

P Dogra, JD Butner, Y Chuang, S Caserta, S Goel… - Biomedical …, 2019 - Springer
Cancer continues to be among the leading healthcare problems worldwide, and efforts
continue not just to find better drugs, but also better drug delivery methods. The need for …

Mechanisms and barriers in cancer nanomedicine: addressing challenges, looking for solutions

TJ Anchordoquy, Y Barenholz, D Boraschi, M Chorny… - 2017 - ACS Publications
Remarkable progress has recently been made in the synthesis and characterization of
engineered nanoparticles for imaging and treatment of cancers, resulting in several …

Mathematical modeling of tumor-immune cell interactions

GE Mahlbacher, KC Reihmer, HB Frieboes - Journal of Theoretical Biology, 2019 - Elsevier
The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

Primary Macrophage-Based Microrobots: An Effective Tumor Therapy In Vivo by Dual-Targeting Function and Near-Infrared-Triggered Drug Release

VD Nguyen, HK Min, HY Kim, J Han, YH Choi… - ACS …, 2021 - ACS Publications
Macrophages (MΦs) have the capability to sense chemotactic cues and to home tumors,
therefore presenting a great approach to engineer these cells to deliver therapeutic agents …

Impact of albumin based approaches in nanomedicine: Imaging, targeting and drug delivery

B Bhushan, V Khanadeev, B Khlebtsov… - Advances in colloid and …, 2017 - Elsevier
Abstracts A major challenge in the field of nanomedicine is to transform laboratory
innovations into commercially successful clinical products. In this campaign, a variety of …

Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues

A Karolak, DA Markov… - Journal of The …, 2018 - royalsocietypublishing.org
A main goal of mathematical and computational oncology is to develop quantitative tools to
determine the most effective therapies for each individual patient. This involves predicting …

Hybrid modeling frameworks of tumor development and treatment

IM Chamseddine, KA Rejniak - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Tumors are complex multicellular heterogeneous systems comprised of components that
interact with and modify one another. Tumor development depends on multiple factors …

Chemically engineered immune cell‐derived microrobots and biomimetic nanoparticles: emerging biodiagnostic and therapeutic tools

LP Jahromi, MA Shahbazi, A Maleki, A Azadi… - Advanced …, 2021 - Wiley Online Library
Over the past decades, considerable attention has been dedicated to the exploitation of
diverse immune cells as therapeutic and/or diagnostic cell‐based microrobots for hard‐to …

Repression of phagocytosis by human CD33 is not conserved with mouse CD33

A Bhattacherjee, E Rodrigues, J Jung… - Communications …, 2019 - nature.com
CD33 is an immunomodulatory receptor linked to Alzheimer's disease (AD) susceptibility via
regulation of phagocytosis in microglia. Divergent features between human CD33 (hCD33) …