[HTML][HTML] Phytochemistry and biological activity of medicinal plants in wound healing: an overview of current research
S Vitale, S Colanero, M Placidi, G Di Emidio, C Tatone… - Molecules, 2022 - mdpi.com
Wound healing is a complicated process, and the effective management of wounds is a
major challenge. Natural herbal remedies have now become fundamental for the …
major challenge. Natural herbal remedies have now become fundamental for the …
[HTML][HTML] Translational implications of CHRFAM7A, an elusive human-restricted fusion gene
Genes restricted to humans may contribute to human-specific traits and provide a different
context for diseases. CHRFAM7A is a uniquely human fusion gene and a negative regulator …
context for diseases. CHRFAM7A is a uniquely human fusion gene and a negative regulator …
[HTML][HTML] Pick-up single-cell proteomic analysis for quantifying up to 3000 proteins in a Mammalian cell
Y Wang, ZY Guan, SW Shi, YR Jiang, J Zhang… - Nature …, 2024 - nature.com
The shotgun proteomic analysis is currently the most promising single-cell protein
sequencing technology, however its identification level of~ 1000 proteins per cell is still …
sequencing technology, however its identification level of~ 1000 proteins per cell is still …
[HTML][HTML] Optogenetic dissection of Rac1 and Cdc42 gradient shaping
Abstract During cell migration, Rho GTPases spontaneously form spatial gradients that
define the front and back of cells. At the front, active Cdc42 forms a steep gradient whereas …
define the front and back of cells. At the front, active Cdc42 forms a steep gradient whereas …
Progress in the therapeutic inhibition of Cdc42 signalling
Cdc42 is a member of the Rho family of small GTPases and a key regulator of the actin
cytoskeleton, controlling cell motility, polarity and cell cycle progression. It signals …
cytoskeleton, controlling cell motility, polarity and cell cycle progression. It signals …
RhoA regulation in space and time
RhoGTPases are well known for being controllers of cell cytoskeleton and share common
features in the way they act and are controlled. These include their switch from GDP to GTP …
features in the way they act and are controlled. These include their switch from GDP to GTP …
[HTML][HTML] “Mitotic slippage” and extranuclear DNA in cancer chemoresistance: A focus on telomeres
K Salmina, A Bojko, I Inashkina, K Staniak… - International journal of …, 2020 - mdpi.com
Mitotic slippage (MS), the incomplete mitosis that results in a doubled genome in interphase,
is a typical response of TP53-mutant tumors resistant to genotoxic therapy. These …
is a typical response of TP53-mutant tumors resistant to genotoxic therapy. These …
[HTML][HTML] Overlapping mechanisms of peripheral nerve regeneration and angiogenesis following sciatic nerve transection
H Wang, H Zhu, Q Guo, T Qian, P Zhang… - Frontiers in cellular …, 2017 - frontiersin.org
Peripheral nervous system owns the ability of self-regeneration, mainly in its regenerative
microenvironment including vascular network reconstruction. More recently, more attentions …
microenvironment including vascular network reconstruction. More recently, more attentions …
Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization
Mobilization of hematopoietic stem cells (HSCs) from bone marrow (BM) to peripheral blood
(PB) by cytokine granulocyte colony-stimulating factor (G-CSF) or the chemical antagonist of …
(PB) by cytokine granulocyte colony-stimulating factor (G-CSF) or the chemical antagonist of …
Epithelial to mesenchymal transition during mammalian neural crest cell delamination
R Zhao, PA Trainor - Seminars in Cell & Developmental Biology, 2023 - Elsevier
Epithelial to mesenchymal transition (EMT) is a well-defined cellular process that was
discovered in chicken embryos and described as “epithelial to mesenchymal …
discovered in chicken embryos and described as “epithelial to mesenchymal …