Phage-based applications in synthetic biology

S Lemire, KM Yehl, TK Lu - Annual review of virology, 2018 - annualreviews.org
Bacteriophage research has been instrumental to advancing many fields of biology, such as
genetics, molecular biology, and synthetic biology. Many phage-derived technologies have …

Molecular basis of bacterial host interactions by Gram-positive targeting bacteriophages

M Dunne, M Hupfeld, J Klumpp, MJ Loessner - Viruses, 2018 - mdpi.com
The inherent ability of bacteriophages (phages) to infect specific bacterial hosts makes them
ideal candidates to develop into antimicrobial agents for pathogen-specific remediation in …

Reporter phage-based detection of bacterial pathogens: design guidelines and recent developments

S Meile, S Kilcher, MJ Loessner, M Dunne - Viruses, 2020 - mdpi.com
Fast and reliable detection of bacterial pathogens in clinical samples, contaminated food
products, and water supplies can drastically improve clinical outcomes and reduce the socio …

Bacteriophages in food applications: From foe to friend

L O'Sullivan, D Bolton, O McAuliffe… - Annual Review of Food …, 2019 - annualreviews.org
Bacteriophages (phages) have traditionally been considered troublesome in food
fermentations, as they are an important cause of starter-culture failure and trigger significant …

Potential of bacteriophage proteins as recognition molecules for pathogen detection

SP Costa, CL Nogueira, AP Cunha… - Critical Reviews in …, 2023 - Taylor & Francis
Bacterial pathogens are leading causes of infections with high mortality worldwide having a
great impact on healthcare systems and the food industry. Gold standard methods for …

Recent progress in the detection of bacteria using bacteriophages: A review

J Paczesny, Ł Richter, R Hołyst - Viruses, 2020 - mdpi.com
Bacteria will likely become our most significant enemies of the 21st century, as we are
approaching a post-antibiotic era. Bacteriophages, viruses that infect bacteria, allow us to …

Catalytic diversity and cell wall binding repeats in the phage‐encoded endolysins

SS Broendum, AM Buckle… - Molecular …, 2018 - Wiley Online Library
Bacteriophage‐encoded endolysins can recognize and bind specific bacteria, and act to
cleave the glycosidic and/or amide bonds in the peptidoglycan (PG) bacterial cell wall …

Exploiting bacteriophage proteomes: the hidden biotechnological potential

SB Santos, AR Costa, C Carvalho, FL Nóbrega… - Trends in …, 2018 - cell.com
Bacteriophages encode many distinct proteins for the successful infection of a bacterial host.
Each protein plays a specific role in the phage replication cycle, from host recognition …

Bacteriophage tail proteins as a tool for bacterial pathogen recognition—a literature review

K Filik, B Szermer-Olearnik, S Oleksy, J Brykała… - Antibiotics, 2022 - mdpi.com
In recent years, a number of bacterial detection methods have been developed to replace
time-consuming culture methods. One interesting approach is to mobilize the ability of …

Wild-type Lactococcus lactis producing bacteriocin-like prophage lysins

TM Takala, S Mokhtari, SL Ahonen, X Wan… - Frontiers in …, 2023 - frontiersin.org
Introduction Lactococcus is a genus of lactic acid bacteria used in the dairy industry as a
starter. Lactococci have been found to produce altogether more than 40 different …